Library Subscription: Guest
Begell Digital Portal Begell Digital Library eBooks Journals References & Proceedings Research Collections
Critical Reviews™ in Neurobiology

ISSN Print: 0892-0915
ISSN Online: 2375-0014

Archives: Volume 10, 1996 to Volume 20, 2008

Critical Reviews™ in Neurobiology

DOI: 10.1615/CritRevNeurobiol.v12.i4.20
pages 305-317

Stress and Brain Angiotensin II Receptors

Tatsuo Watanabe
The Department of Physiology, Yamaguchi University School of Medicine, Llbe Yamaguchi 755, Japan
Takashi Fujioka
The Department of Physiology, Yamaguchi University School of Medicine, Llbe Yamaguchi 755, Japan
Makoto Hashimoto
Department of Otolaryngology, Yamaguchi University School of Medicine, Llbe Yamaguchi 755, Japan
Shoji Nakamura
The Department of Physiology, Yamaguchi University School of Medicine, Llbe Yamaguchi 755, Japan

ABSTRACT

Angiotensin II (ANGII) has been recognized recently as one of the stress hormones that participate in various stress-induced responses, including sympathetic (pressor, tachycardiac, and hyperthermic) and neuroendocrine responses. Brain ANG II receptors have been identified in many brain regions involved in the stress responses. During stress-exposure, ANG II increases in the plasma and in the brain. Central administration of ANG II induces stress responses, whereas central blockade of ANG II receptors results in the inhibition of the sympathetic and neuroendocrine responses to stress. All these findings indicate that ANG II and its receptors contribute to the development of various sympathetic and neuroendocrine responses during stress exposure. This review focuses on the role of brain ANG II receptors in the stress-induced responses.


Articles with similar content:

Regulation of Cannabinoid CB1 Receptors in the Central Nervous System by Chronic Cannabinoids
Critical Reviews™ in Neurobiology, Vol.15, 2003, issue 2
Laura J. Sim-Selley
Nitric Oxide in Cerebral Ischemic Neurodegeneration and Excitotoxicity
Critical Reviews™ in Neurobiology, Vol.12, 1998, issue 3
Paul J. L. M. Strijbos
Hedgehog Signaling in Hematopoiesis
Critical Reviews™ in Eukaryotic Gene Expression, Vol.20, 2010, issue 2
Yiting Lim , William Matsui
Endocannabinoid Signaling and Synaptic Plasticity in the Brain
Critical Reviews™ in Neurobiology, Vol.18, 2006, issue 1-2
Ping Jun Zhu
Pharmacology of Endogenous Neuroactive Steroids
Critical Reviews™ in Neurobiology, Vol.15, 2003, issue 3&4
Doodipala Samba Reddy