RT Journal Article
ID 164dfa766d4c8f0b
A1 Ayala-Zavala, Jesus Fernando
A1 Perez-Carlon, Julio Jesumar
A1 Esqueda, Martin
A1 Gonzalez-Aguilar, Gustavo Adolfo
A1 Leyva, Juan Manuel
A1 Cruz-Valenzuela, Manuel Reynaldo
A1 Moctezuma, Edgar
T1 Polar Fractionation Affects the Antioxidant Properties of Methanolic Extracts from Species of Genus Phellinus Quel. (Higher Basidiomycetes)
JF International Journal of Medicinal Mushrooms
JO IJM
YR 2012
FD 2012-12-14
VO 14
IS 6
SP 563
OP 573
K1 medicinal mushrooms
K1 antioxidant activity
K1 Phellinus species
K1 extraction
K1 phenolic compounds
AB The main objective of this study was to evaluate the antioxidant capacity of methanolic extracts from species of genus Phellinus: Ph. fastuosus, Ph. grenadensis, Ph. Merrillii, and Ph. Badius, in their respective polar fractions (aqueous) and nonpolar extracts (ethyl acetate), through tests of free-radical inactivation and hemolysis inhibition. The fungus species that gave the extract with the highest phenol content, total flavonoids, and antioxidant capacity [DPPH·, Trolox equivalents antioxidant capacity (TEAC), and hemolysis inhibition] was Ph. Merrillii, followed by Ph. fastuosus, Ph. Grenadensis, and Ph. Badius. The antioxidant capacities of the extracts, in descending order, were as follows: Ph. Merrillii (nonpolar), Ph. Fastuosus (nonpolar), Ph. Grenadensis (nonpolar), Ph. Fastuosus (polar), Ph. Merrillii (polar), Ph. Grenadensis (polar), Ph. Badius (nonpolar), and Ph. Badius (polar). Antioxidant capacity in the above Phellinus fungi species had EC50 values for DPPH inhibition of 0.45, 0.88, 1.31, 1.89, 2.14, 2.22, 3.42, and 6.00 mg/mL, respectively; TEAC values of 10400.29, 7635.53, 4855.05, 4415.39, 4041.68, 2989.2, 1937.7, and 842.42 µmol TE/g, respectively; and hemolysis inhibition values of 72.83, 66.95, 50.87, 50.28, 48.5, 42.82, 42.37, and 37.91%, respectively. In general, the fungus extract with the highest antioxidant capacity was the nonpolar fraction of Ph. Merrillii. The Phellinus species studied represent potential natural sources of bioactive compounds with antioxidant activity.
PB Begell House
LK https://www.dl.begellhouse.com/journals/708ae68d64b17c52,33e1986c385c2cd3,164dfa766d4c8f0b.html