RT Journal Article ID 3c886bce7d9909c9 A1 Khadhri, Ayda A1 Aouadhi, Chedia A1 Aschi-Smiti, Samira T1 Screening of Bioactive Compounds of Medicinal Mushrooms Collected on Tunisian Territory JF International Journal of Medicinal Mushrooms JO IJM YR 2017 FD 2017-04-20 VO 19 IS 2 SP 127 OP 135 K1 antimicrobial activity K1 antioxidant activity K1 medicinal mushrooms K1 phenolic content AB This study is, to our knowledge, the first to investigate the pharmacological importance of wild Tunisian mushrooms. Ethanolic extracts of 5 Tunisian mushrooms−Phellinus torulosus, Fomes fomentarius, Trametes versicolor, Pisolithus albus, and Fomitopsis pinicola−were collected from the Kroumirie Region (North Tunisia). The dry basidomes of mushrooms were extracted using ethanol and evaluated for total polyphenol, flavonoid, flavonol, tannin, proanthocyanidin, and anthocyanin content. In addition, their antioxidant activities were determined using 3 assays (testing 2,2-diphenyl-1-picrylhydrazyl [DPPH] radical scavenging, the reducing power of iron, and the iron-chelating power). Their antimicrobial activities were assessed against 8 bacterial species. The results revealed the presence of significant differences between the secondary metabolites and biological activities of the different tested extracts. In addition, significant correlations were observed between antioxidant activities and phenolic contents. Crude ethanol extracts prepared from basidomes of F. fomentarius and Ph. torulosus have higher total phenolic content and antioxidant activity per the DPPH and metal-chelating activity assays. The reducing power assay showed that the ethanolic extract of F. pinicola had the highest activity. Ethanolic extracts of the 5 mushrooms have antibacterial activity against the evaluated strains. PB Begell House LK https://www.dl.begellhouse.com/journals/708ae68d64b17c52,44050ca75c27d781,3c886bce7d9909c9.html