RT Journal Article
ID 434b319e56f744f7
A1 Harguindey, Salvador
A1 Pedraz, Jose Luis 
A1 Canero, Rafael Garcia 
A1 de Diego, Javier Perez 
A1 Cragoe, Jr., Edward J. 
T1 Hydrogen Ion-Dependent Oncogenesis and Parallel New Avenues to Cancer Prevention and Treatment Using a H<sup>&#43;</sup>-Mediated Unifying Approach: pH-Related and pH-Unrelated Mechanisms
JF Critical Reviews&trade; in Oncogenesis
JO CRO
YR 1995
FD 1995-03-01
VO 6
IS 1
SP 1
OP 34
K1 oncogenes
K1 oncogenesis
K1 gene transcription
K1 Na<sup>&#43;</sup>/H<sup>&#43;</sup> antiporter
K1 cancer prevention
K1 cancer treatment
K1 ATPases and cancer
K1 spontaneous regression of cancer.
AB A comprehensive examination of phenomena related to cancer is presented that is based on hydrogen ion dynamics, as viewed from the biological, biochemical, and biophysical perspective. A model is described that considers an array of cancer-associated events from oncogenesis to carcinogenesis from this perspective. The basic ideas are viewed from various aspects, ranging from the cellular level to the clinical situation. The novel types of therapeutic and prophylactic agents that result from applying these concepts are elucidated. Considerable insight into this modern approach is seen from some of the mechanisms that characterize the phenomenon of spontaneous regression of cancer.
PB Begell House
LK https://www.dl.begellhouse.com/journals/439f422d0783386a,6a55d76628d7bc95,434b319e56f744f7.html