RT Journal Article ID 688729963a3677b9 A1 Liang, Bojian A1 Fujibayashi, Shunsuke A1 Fujita, Hiroshi A1 Ise, Kentaro A1 Neo, Masashi A1 Nakamura, Takashi T1 Long-Term Follow-Up Study of Bioactive Bone Cement in Canine Total Hip Arthroplasty JF Journal of Long-Term Effects of Medical Implants JO JLT YR 2006 FD 2006-08-31 VO 16 IS 4 SP 291 OP 300 AB We report a long-term study of bioactive bone cement (BABC) in a canine total hip arthroplasty (THA) at follow-up of 8 years. Previous studies have shown excellent biomechanical and histological results at follow-up of 6, 12, and 24 months. In the present study, THA was performed in a beagle dog using BABC consisting of an apatite- and wollastonite-containing glass ceramic (AW-GC) powder and SiO2 powder as the filler and a bisphenol-a-glycidyl methacrylate (Bis-GMA) based resin as the organic matrix. Histological examination showed direct bonding between BABC and bone without any intervening soft tissue layer at the BABC-bone interface. A reactive layer, through which BABC bonded to the bone, was observed thicker at 8 years than it was at 24 weeks. No adverse effects of BABC were observed. BABC maintained the high bioactivity and direct bonding to bone in a canine THA at follow-up of 8 years. PB Begell House LK https://www.dl.begellhouse.com/journals/1bef42082d7a0fdf,2079c9ee5d0479b2,688729963a3677b9.html