RT Journal Article ID 7ec883303ae32790 A1 Sharma, Rahul A1 Singh, Harmanpreet A1 Joshi, Munish A1 Sharma, Abhinandan A1 Garg, Tarun A1 Goyal, Amit A1 Rath, Goutam T1 Recent Advances in Polymeric Electrospun Nanofibers for Drug Delivery JF Critical Reviews™ in Therapeutic Drug Carrier Systems JO CRT YR 2014 FD 2014-05-16 VO 31 IS 3 SP 187 OP 217 K1 electrospinning K1 nanofiber K1 drug delivery K1 polymers AB Electrospinning is a simple unit operation process by which polymeric nanofibers with diameters ranging from a few nanometers to hundreds of micrometers can be fabricated using an electrostatically operated jet of polymer solution or polymer melt. Nanofibers because of their interesting features, such as surface-to-volume ratio, high surface area, microporosity, and nonwoven structure, provide numerous opportunities to design novel carrier systems for large commodities of therapeutics. Physicochemical properties of nanofibers depend on several process and formulation parameters, such as applied voltage, flow rate, polymer selection, and concentration of polymer used. The applications of nanofibers in drug delivery are nearly unbounded. This review summarizes the most recent work done on the various physicochemical parameters of electrospinning and polymers used in making wide varieties of nanofibers along with their role in developing more effective, novel drug delivery systems. PB Begell House LK https://www.dl.begellhouse.com/journals/3667c4ae6e8fd136,5461787910441df1,7ec883303ae32790.html