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Nanoscience and Technology: An International Journal

年間 4 号発行

ISSN 印刷: 2572-4258

ISSN オンライン: 2572-4266

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.3 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.7 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.7 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00023 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.11 SJR: 0.244 SNIP: 0.521 CiteScore™:: 3.6 H-Index: 14

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THE USE OF NANOSORBENTS AND FRACTIONATION TECHNIQUES IN LIFE SUPPORT SYSTEMS

巻 5, 発行 1, 2014, pp. 73-84
DOI: 10.1615/NanomechanicsSciTechnolIntJ.v5.i1.60
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要約

This research is devoted to the search of effective methods required for life support during long expeditions and follow-up rehabilitation, in particular, for biologic fluid clarification. The possibility of using filtration methods, including centrifugation (g factors: 1500, 1600 or 11,300), micro- (0.22 μm) and ultrafiltration (67 kD), as well as nanoparticles of magnetite Fe3O4, synthesized by a polymer-mediated method in a matrix of humic and pectic acids by in situ chemical codeposition of ferrous and ferric iron chloride in the NH4OH medium as biocompatible nanosorbents of lymph ingredients, is demonstrated. The work presents some results of structural investigations of nanoparticles using scanning electron microscopy and X-ray phase analysis. The mean size of particles, calculated by the Scherrer equation, as well as according to electronic microcopy data makes ~16 nm for Fe3O4/HA and ~14 nm for Fe3O4/Pec. As controlled criteria of efficiency and mechanical processing and the sorption capacity we used the biochemical indicators of the content of their basic constant ingredient in lymph, the level of concentration of which can be used to evaluate the condition of cellular, organic, and general homeostasis at different diseases.
It is demonstrated that mechanical processing (centrifugation and membrane filtration) allows a significant decrease − several times for some ingredients − of the investigated protein and lipid lymph components (in particular, the content of alanine aminotransferase reduced 20 times, of aspartate aminotransferase three times, of total cholesterol eight times, of creatinine six times, of total protein four times, and of albumin 10 times compared to the reference data) to their normal values. However, the content of glucose remains invariable for these methods of processing.
The investigations of the sorption characteristics of magnetite nanoparticles to lymph components, functionalized by natural biocompatible polymers, demonstrated that the introduction of sorbents leads to sorption of actually all lymph components on their surface, with the exception of bilirubin. The content of lymph components decreased by 50% or more, compared to the original sample. The values of the steady-state concentration of lymph components after their sorption on the Fe3O4/HA surface are much higher than the relevant values for the composite based on pectin Fe3O4/Pec. The results of these investigations require further studies of conditions and techniques of liquid separation, thorough evaluation of stability and toxicity of modified nanoparticles, and a greater sample of biological fluid preparations.

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