ライブラリ登録: Guest
Critical Reviews™ in Immunology

年間 6 号発行

ISSN 印刷: 1040-8401

ISSN オンライン: 2162-6472

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.3 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.6 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00079 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.24 SJR: 0.429 SNIP: 0.287 CiteScore™:: 2.7 H-Index: 81

Indexed in

Macrophage Migration Inhibitory Factor (MIF): A Glucocorticoid Counter-Regulator within the Immune System

巻 37, 発行 2-6, 2017, pp. 381-391
DOI: 10.1615/CritRevImmunol.v37.i2-6.90
Get accessGet access

要約

Originally described as a T lymphocyte-derived factor that inhibited the random migration of macrophages, the protein known as macrophage migration inhibitory factor (MIF) was an enigmatic cytokine for almost 3 decades. In recent years, the discovery of MIF as a product of the anterior pituitary gland and the cloning and expression of bioactive, recombinant MIF protein have led to the definition of its critical biological role in vivo. MIF has the unique property of being released from macrophages and T lymphocytes that have been stimulated by glucocorticoids. Once released, MIF overcomes the inhibitory effects of glucocorticoids on TNFα, IL-1β, IL-6, and IL-8 production by LPS-stimulated monocytes in vitro and suppresses the protective effects of steroids against lethal endotoxemia in vivo. MIF also antagonizes glucocorticoid inhibition of T-cell proliferation in vitro by restoring IL-2 and IFN-γ production. This observation has identified a pivotal role for MIF within the immune system and fills an important gap in our understanding of the control of inflammatory and immune responses. Glucocorticoids have long been considered to be an integral component of the stress response to infection or tissue invasion and serve to modulate inflammatory and immune responses. MIF is the first mediator to be identified that can counter-regulate the inhibitory effects of glucocorticoids and thus plays a critical role in the host control of inflammation and immunity.

によって引用された
  1. Zhu Wen-Yan, Jin Xin, Ma Yong-Chi, Liu Zhi-Biao, Correlations of MIF polymorphism and serum levels of MIF with glucocorticoid sensitivity of sudden sensorineural hearing loss, Journal of International Medical Research, 48, 4, 2020. Crossref

  2. Boutaoui Nadia, Puranik Sandeep, Zhang Rong, Wang Ting, Hui Daniel H., Brehm John, Forno Erick, Chen Wei, Celedón Juan C., Epigenome-wide effects of vitamin D on asthma bronchial epithelial cells, Epigenetics, 14, 9, 2019. Crossref

  3. Schmid Nina, Flenkenthaler Florian, Stöckl Jan B., Dietrich Kim-Gwendolyn, Köhn Frank M., Schwarzer J. Ullrich, Kunz Lars, Luckner Manja, Wanner Gerhard, Arnold Georg J., Fröhlich Thomas, Mayerhofer Artur, Insights into replicative senescence of human testicular peritubular cells, Scientific Reports, 9, 1, 2019. Crossref

  4. Losada-Barragán Monica, Umaña-Pérez Adriana, Rodriguez-Vega Andrés, Cuervo-Escobar Sergio, Azevedo Renata, Morgado Fernanda N., de Frias Carvalho Vinicius, Aquino Priscila, Carvalho Paulo C., Porrozzi Renato, Sánchez-Gómez Myriam, Padron Gabriel, Cuervo Patricia, Proteomic profiling of splenic interstitial fluid of malnourished mice infected with Leishmania infantum reveals defects on cell proliferation and pro-inflammatory response, Journal of Proteomics, 208, 2019. Crossref

  5. Bozza Marcelo T., Lintomen Leticia, Kitoko Jamil Z., Paiva Cláudia N., Olsen Priscilla C., The Role of MIF on Eosinophil Biology and Eosinophilic Inflammation, Clinical Reviews in Allergy & Immunology, 58, 1, 2020. Crossref

  6. Gow Debbie J, Jackson Hilary, Forsythe Peter, Gow Adam G, Mellanby Richard J, Hume David A, Nuttall Tim, Measurement of serum macrophage migration inhibitory factor (MIF) and correlation with severity and pruritus scores in client owned dogs with atopic dermatitis, Veterinary Dermatology, 30, 2, 2019. Crossref

  7. Haitjema Saskia, Hoefer Imo E., When the Myocardium Gets MIFfed: Macrophage Inhibitory Factor as a Biomarker in Acute Coronary Artery Disease, Canadian Journal of Cardiology, 35, 10, 2019. Crossref

  8. Yang Minggen, Xu Zhenqiang, Zhuang Zhiming, Macrophages affect immune inflammation and proliferation in benign prostatic hyperplasia via androgen receptor and CD40/CD40L signaling pathway, Tissue and Cell, 64, 2020. Crossref

  9. Šošić-Jurjević Branka, Ajdžanović Vladimir, Miljić Dragana, Trifunović Svetlana, Filipović Branko, Stanković Sanja, Bolevich Sergey, Jakovljević Vladimir, Milošević Verica, Pituitary Hyperplasia, Hormonal Changes and Prolactinoma Development in Males Exposed to Estrogens—An Insight From Translational Studies, International Journal of Molecular Sciences, 21, 6, 2020. Crossref

  10. Do Jong Geol, Noh Sun Up, Chae Seoung Wan, Yoon Kyung Jae, Lee Yong-Taek, Excessive walking exercise precipitates diabetic neuropathic foot pain: hind paw suspension treadmill exercise experiment in a rat model, Scientific Reports, 10, 1, 2020. Crossref

  11. Wang Qing‑Hua , Zhang Min , Zhou Ming‑Hui , Gao Xiao‑Jiao , Chen Fang , Yan Xun , Lu Feng , High expression of eukaryotic initiation factor�3M predicts poor prognosis in colon adenocarcinoma patients, Oncology Letters, 2019. Crossref

  12. Jovanović Krivokuća Milica, Stefanoska Ivana, Vilotić Aleksandra, Ćujić Danica, Vrzić Petronijević Svetlana, Vićovac Ljiljana, Macrophage migration inhibitory factor modulates cytokine expression in the trophoblast cell line HTR-8/SVneo, Reproduction, Fertility and Development, 32, 18, 2020. Crossref

  13. Chen Xi, Chen Yifan, Qi Dake, Cui Donghong, Multifaceted interconnections between macrophage migration inhibitory factor and psychiatric disorders, Progress in Neuro-Psychopharmacology and Biological Psychiatry, 112, 2022. Crossref

  14. Harjacek Miroslav, Immunopathophysiology of Juvenile Spondyloarthritis (jSpA): The “Out of the Box” View on Epigenetics, Neuroendocrine Pathways and Role of the Macrophage Migration Inhibitory Factor (MIF), Frontiers in Medicine, 8, 2021. Crossref

  15. Benedek Gil, Abed El Latif Mahmoud, Miller Keren, Rivkin Mila, Ahmed Ramadhan Lasu Ally, P. Riek Lul, Lako Richard, Edvardson Shimon, Arbel-Alon Sagit, Galun Eithan, Levite Mia, Gómez-Morales Maria Angeles, Macrophage migration inhibitory factor in Nodding syndrome, PLOS Neglected Tropical Diseases, 15, 10, 2021. Crossref

  16. Varyani Fumi, Löser Stephan, Filbey Kara J., Harcus Yvonne, Drurey Claire, Poveda Marta Campillo, Rasid Orhan, White Madeleine P. J., Smyth Danielle J., Gerbe François, Jay Philippe, Maizels Rick M., The IL-25-dependent tuft cell circuit driven by intestinal helminths requires macrophage migration inhibitory factor (MIF), Mucosal Immunology, 2022. Crossref

  17. Teipel Stefan J., Dyrba Martin, Ballarini Tommaso, Brosseron Frederic, Bruno Davide, Buerger Katharina, Cosma Nicoleta-Carmen, Dechent Peter, Dobisch Laura, Düzel Emrah, Ewers Michael, Fliessbach Klaus, Haynes John D., Janowitz Daniel, Kilimann Ingo, Laske Christoph, Maier Franziska, Metzger Coraline D., Munk Matthias H., Peters Oliver, Pomara Nunzio, Preis Lukas, Priller Josef, Ramírez Alfredo, Roy Nina, Scheffler Klaus, Schneider Anja, Schott Björn H., Spottke Annika, Spruth Eike J., Wagner Michael, Wiltfang Jens, Jessen Frank, Heneka Michael T., Association of Cholinergic Basal Forebrain Volume and Functional Connectivity with Markers of Inflammatory Response in the Alzheimer’s Disease Spectrum, Journal of Alzheimer's Disease, 85, 3, 2022. Crossref

  18. Vukićević Dušan, Rovčanin Branislav, Gopčević Kristina, Stanković Sanja, Vučević Danijela, Jorgačević Bojan, Mladenović Dušan, Vesković Milena, Samardžić Janko, Ješić Rada, Radosavljević Tatjana, The Role of MIF in Hepatic Function, Oxidative Stress, and Inflammation in Thioacetamide-induced Liver Injury in Mice: Protective Effects of Betaine, Current Medicinal Chemistry, 28, 16, 2021. Crossref

  19. Kong Yao-Zhong, Chen Qiyan, Lan Hui-Yao, Macrophage Migration Inhibitory Factor (MIF) as a Stress Molecule in Renal Inflammation, International Journal of Molecular Sciences, 23, 9, 2022. Crossref

  20. Arnold Amanda R., Chassaing Benoit, Pearce Bradley D., Huhman Kim L., Dietary emulsifier consumption alters gene expression in the amygdala and paraventricular nucleus of the hypothalamus in mice, Scientific Reports, 12, 1, 2022. Crossref

  21. Cho Young-Duck, Choi Sung-Hyuk, Park Sung-Jun, Kim Jung-Youn, Lim Chae-Seung, Yu Woo-Sung, Kyung Hwan Kim, Shin Tae-Gun, The impacts of oxygen and pentoxifylline in hypoxic condition, European Journal of Inflammation, 20, 2022. Crossref

  22. Lebold Katie M., Drake Matthew G., Pincus Alexandra B., Pierce Aubrey B., Fryer Allison D., Jacoby David B., Unique Allergic Asthma Phenotypes in Offspring of House Dust Mite–exposed Mice, American Journal of Respiratory Cell and Molecular Biology, 67, 1, 2022. Crossref

  23. Wu Kai-Min, Zhang Ya-Ru, Huang Yu-Yuan, Dong Qiang, Tan Lan, Yu Jin-Tai, The role of the immune system in Alzheimer’s disease, Ageing Research Reviews, 70, 2021. Crossref

  24. Stošić-Grujičić Stanislava, Saksida Tamara, Miljković Đorđe, Stojanović Ivana, MIF and insulin: Lifetime companions from common genesis to common pathogenesis, Cytokine, 125, 2020. Crossref

  25. Thapa Komal, Khan Heena, Sharma Uma, Grewal Amarjot Kaur, Singh Thakur Gurjeet, Poly (ADP-ribose) polymerase-1 as a promising drug target for neurodegenerative diseases, Life Sciences, 267, 2021. Crossref

  26. Juárez-Avelar Imelda, Rodríguez Tonathiu, García-García Ana P., Rodríguez-Sosa Miriam, Macrophage migration inhibitory factor (MIF): Its role in the genesis and progression of colorectal cancer, in Immunotherapy in Resistant Cancer: From the Lab Bench Work to Its Clinical Perspectives, 2021. Crossref

  27. Ding Na, Li Peng-Lei, Wu Kai-Li, Lv Tie-Gang, Yu Wen-Lu, Hao Jian, Macrophage migration inhibitory factor levels are associated with disease activity and possible complications in membranous nephropathy, Scientific Reports, 12, 1, 2022. Crossref

近刊の記事

Identification of a novel five-gene prognostic model for laryngeal cancer associated with mitophagy using integrated bioinformatics analysis and experimental verification Dong Song, Lun Dong, Mei Wang, Xiaoping Gao Function of steroid receptor coactivators (SRCs) in T cells and cancers: Implications for cancer immunotherapy Wencan Zhang, Xu Cao, Hongmin Wu, Xiancai Zhong, Yun Shi, Zuoming Sun Electroacupuncture Alleviates Ischemic Stroke by Activating the mTOR/SREBP1 Pathway Jiawang Lang, Jianchang Luo, Luodan Wang, Wenbin Xu, Jie Jia, Zhipeng Zhao, Boxu Lang KIAA1429 induces the m6A modification of LINC01106 to enhance the malignancy of lung adenocarcinoma cell via JAK/STAT3 pathway Di Xu, Ziming Wang, Fajiu Li Effect of p-estrogen receptor at serine on its function and breast growth Yuan Liang, Junhui Qin, Tiancheng Ma, Tong Yang, Zhenyu Ke, Ruian Wang Mechanistic Insights into Tanshinone IIA in the Amelioration of Post-Thyroidectomy Hypoparathyroidism Xiaoyu Qian, Lin Li, Liang Chen, Chao Shen, Jian Tang MiRNA let-7d-5p alleviates inflammatory responses by targeting Map3k1 and inactivating ERK/p38 MAPK signaling in microglia Fan Fang, Cheng Chen Role of Natural Killer Cells as Cell-Based Immunotherapy in Oral Tumor Eradication and Differentiation Both In Vivo and In Vitro Kawaljit Kaur, Anahid Jewett The Current and Future States of Natural Killer Cell-Based Immunotherapy in Hepatocellular Carcinoma Tu Nguyen, Po-Chun Chen, Janet Pham, Kawaljit Kaur, Steven Raman, Anahid Jewett, Jason Chiang Phillygenin alleviated arthritis through the inhibition of NLRP3 inflammasome and Ferroptosis by AMPK Jianghui Wang, Shufang Ni, Kai Zheng, Yan Zhao, peihong zhang, Hong Chang The value of systemic immune-inflammation index and T cell subsets in the severity and prognosis of sepsis Hao Zhou Efficacy and Nuances of Precision Molecular Engineering for Hodgkin's Disease to a Gene Therapeutic Approach Muhammad Imran Qadir, Bilal Ahmed, Nadir Hussain Serum interleukin 6 and ferritin levels are the independent risk factors for pneumonia in elderly patients Hao Yuan, Jing Tian, Lu Wen Exploration of diagnostic markers associated with inflammation in chronic kidney disease (CKD) based on WGCNA and machine learning Qianjia Wu, Yang Yang, Chongze Lin Clinical significance of serum CTRP3 level in the prediction of cardiac dysfunction and intestinal mucosal barrier dysfunction in patients with severe acute pancreatitis Qiang Shao, Lin Sun The protective effect and mechanism of mild hypothermia on pig lung injury after cardiopulmonary resuscitation Jinlin Ren, Fangfang Zhu, Dongdong Sang, Mulin Cong, Shujuan Jiang Exploring mechanism of Zilongjin in treating lung adenocarcinoma based on network pharmacology combined with experimental verification Kang Zhang, Xiaoqun Chen Gastric Cancer Immune Subtypes and Prognostic Modeling: Insights from Aging-Related Genes Analysis Jian Shen, Minzhe Li Effects of different doses of dexmedetomidine on the prevention of postoperative sleep disturbance and serum neurotransmitter level in patients under general anesthesia Huifei Lu, Fei He, Ying Huang, Zhongliang Wei Identification of key ubiquitination-related genes and their associated with immune infiltration in osteoarthritis based on mRNA-miRNA network Dalu Yuan, Hailiang Shen, Lina Bai, Menglin Li, Qiujie Ye Diagnostic and Prognostic value of peripheral neutrophil CD64 index in elderly patients with community-acquired pneumonia Yan Li, Jing Zhang, Suhang Wang, Jie Cao Identification of Metabolism-Related Prognostic Biomarkers and Immune Features of Head and Neck Squamous Cell Carcinoma Rongjin Zhou, Junguo Wang Downregulation of miR-503-5p promotes the development of pancreatic cancer via targeting cyclin E2 Fei Li, Ying-pei Ling, Pan Wang, Shi-cheng Gu, Hao Jiang, Jie Zhu
Begell Digital Portal Begellデジタルライブラリー 電子書籍 ジャーナル 参考文献と会報 リサーチ集 価格及び購読のポリシー Begell House 連絡先 Language English 中文 Русский Português German French Spain