ライブラリ登録: Guest
Begell Digital Portal Begellデジタルライブラリー 電子書籍 ジャーナル 参考文献と会報 リサーチ集
Critical Reviews™ in Therapeutic Drug Carrier Systems
インパクトファクター: 2.9 5年インパクトファクター: 3.72 SJR: 0.736 SNIP: 0.818 CiteScore™: 4.6

ISSN 印刷: 0743-4863
ISSN オンライン: 2162-660X

巻:
巻 37, 2020 巻 36, 2019 巻 35, 2018 巻 34, 2017 巻 33, 2016 巻 32, 2015 巻 31, 2014 巻 30, 2013 巻 29, 2012 巻 28, 2011 巻 27, 2010 巻 26, 2009 巻 25, 2008 巻 24, 2007 巻 23, 2006 巻 22, 2005 巻 21, 2004 巻 20, 2003 巻 19, 2002 巻 18, 2001 巻 17, 2000 巻 16, 1999 巻 15, 1998 巻 14, 1997 巻 13, 1996 巻 12, 1995

Critical Reviews™ in Therapeutic Drug Carrier Systems

DOI: 10.1615/CritRevTherDrugCarrierSyst.v26.i1.20
pages 29-84

Recent Developments of Biodegradable and Biocompatible Materials Based Micro/Nanoparticles for Delivering Macromolecular Therapeutics

Yang Shi
Pharmaceutical College, Shandong University, Ji'nan 250012, China
Guihua Huang
Pharmaceutical College, Shandong University, Ji'nan 250012, China

要約

Developments in biotechnology have seen the growing use of macromolecules containing proteins, peptides, vaccines, antigens, genes, and growth factors as therapeutic agents. Because these macromolecules are easily denatured and metabolized rapidly in vivo, their protection and controlled release are required. Biodegradable and biocompatible materials based micro/nanoparticles (MPs/NPs) show great potential for delivering macromolecular therapeutics. One of the greatest challenges in the delivery of macromolecules from biodegradable and biocompatible MPs/NPs is the controlled and complete release of the drugs in their native forms. Unfortunately, the present drug delivery systems cannot satisfy the requirement; thus, more research is expected. This article discusses the recent developments in the field of macromolecular delivery.


Articles with similar content:

Multifunctional Matrices for Oral Peptide Delivery
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.18, 2001, issue 5
Andreas Bernkop-Schnurch, Greg Walker
Advanced Implantable Drug Delivery Systems via Continuous Manufacturing
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.33, 2016, issue 6
Ali Nokhodchi, Mohammed Maniruzzaman
Recent Advances in Self-Emulsifying Drug Delivery Systems (SEDDS)
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.31, 2014, issue 2
Premjeet Singh Sandhu, Ravinder Kaur, Sarwar Beg, Bhupinder Singh, Om Parkash Katare, Rajneet Kaur Khurana
Lipid-Based Nanoparticles as Pharmaceutical Drug Carriers: From Concepts to Clinic
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.26, 2009, issue 6
Eliahu Heldman, Kristin Loomis, Brandon Smith, Anu Puri, Jae-Ho Lee, Amichai Yavlovich, Robert Blumenthal
Lipid Nanoparticles for Nasal/Intranasal Drug Delivery
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.34, 2017, issue 3
S. Cunha, M. H. Amaral, J. M. Sousa Lobo, Ana C. Silva