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Critical Reviews™ in Therapeutic Drug Carrier Systems

年間 6 号発行

ISSN 印刷: 0743-4863

ISSN オンライン: 2162-660X

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.7 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 3.6 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.8 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00023 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.39 SJR: 0.42 SNIP: 0.89 CiteScore™:: 5.5 H-Index: 79

Indexed in

Topotecan Liposomes: A Visit from a Molecular to a Therapeutic Platform

巻 33, 発行 5, 2016, pp. 401-432
DOI: 10.1615/CritRevTherDrugCarrierSyst.2016015926
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要約

Topotecan (TPT), a potent anticancer camptothecin analog, is well described for the treatment of ovarian cancer, but has also anticancer activity against small-cell and non-small-cell lung cancer, breast cancer, and acute leukemia. Various nanocarriers, including liposomes, have been exploited for targeted delivery of TPT. However, there are a number of challenges with TPT delivery using TPT liposomes (TLs), such as low encapsulation efficiency, physiological pH labile E ring (hydrolysis), accelerated blood clearance, multidrug resistance, and cancer metastases. This review discusses these problems and the means to overcome them, including modification of TLs using zwitterionic poly(carboxybetaine), prolongation in dosing interval (long-term therapy), and modified liposomal encapsulation techniques including active loading methods. We also explore engineered TLs (surface and integral modifications) such as PEGylated TLs, ligand-anchored TLs, and stimuli-sensitive TLs. Further, potential applications, manifestations at the molecular level, patents granted, and preclinical and clinical outlook for TLs are discussed.

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  1. Jain Ankit, Tiwari Ankita, Verma Amit, Jain Sanjay K., Ultrasound-based triggered drug delivery to tumors, Drug Delivery and Translational Research, 8, 1, 2018. Crossref

  2. Jain Ankit, Jain Sanjay K., Application Potential of Engineered Liposomes in Tumor Targeting, in Multifunctional Systems for Combined Delivery, Biosensing and Diagnostics, 2017. Crossref

  3. Jain Sanjay Kumar, Tiwari Ankita, Jain Ankit, Verma Amit, Saraf Shivani, Panda Pritish Kumar, Gour Gaytri, Application Potential of Polymeric Nanoconstructs for Colon-Specific Drug Delivery, in Multifunctional Nanocarriers for Contemporary Healthcare Applications, 2018. Crossref

  4. Pinna Roberto, Filigheddu Enrica, Juliano Claudia, Palmieri Alessandra, Manconi Maria, D’hallewin Guy, Petretto Giacomo, Maioli Margherita, Caddeo Carla, Manca Maria Letizia, Solinas Giuliana, Bortone Antonella, Campanella Vincenzo, Milia Egle, Antimicrobial Effect of Thymus capitatus and Citrus limon var. pompia as Raw Extracts and Nanovesicles, Pharmaceutics, 11, 5, 2019. Crossref

  5. Jain Ankit, Prajapati Shiv Kumar, Kumari Amrita, Mody Nishi, Bajpai Meenakshi, Engineered nanosponges as versatile biodegradable carriers: An insight, Journal of Drug Delivery Science and Technology, 57, 2020. Crossref

  6. Saraf Shivani, Jain Ankit, Tiwari Ankita, Verma Amit, Panda Pritish Kumar, Jain Sanjay K., Advances in liposomal drug delivery to cancer: An overview, Journal of Drug Delivery Science and Technology, 56, 2020. Crossref

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  8. Shastri Madhur D., Chong Wai Chin, Dua Kamal, Peterson Gregory M., Patel Rahul P., Mahmood Malik Q., Tambuwala Murtaza, Chellappan Dinesh K., Hansbro Nicole G., Shukla Shakti D., Hansbro Philip M., Emerging concepts and directed therapeutics for the management of asthma: regulating the regulators, Inflammopharmacology, 29, 1, 2021. Crossref

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  10. Saraf Shivani, Jain Ankit, Tiwari Ankita, Verma Amit, Jain Sanjay K., Engineered liposomes bearing camptothecin analogue for tumour targeting: in vitro and ex-vivo studies, Journal of Liposome Research, 31, 4, 2021. Crossref

  11. Lee Jaeok, Kang Jiyeon, Kwon Na-Yun, Sivaraman Aneesh, Naik Ravi, Jin So-Young, Oh A. Reum, Shin Jae-Ho, Na Younghwa, Lee Kyeong, Lee Hwa-Jeong, Dual Inhibition of P-gp and BCRP Improves Oral Topotecan Bioavailability in Rodents, Pharmaceutics, 13, 4, 2021. Crossref

  12. Jain Ankit, Tripathi Madhavi, Prajapati Shiv K., Raichur Ashok M., Biopolymer Matrix Composite for Drug Delivery Applications in Cancer, in Encyclopedia of Materials: Composites, 2021. Crossref

  13. Akhtar Naseem, Mohammed Salman AA, Singh Varsha, Abdellatif Ahmed AH, Mohammad Hamdoon A, Ahad Abdul, Yusuf Mohammad, Khadri Habeeb, Naz Mamuna, Khan Omar, Rashid Mohammad, Khan Riaz A, Liposome-based drug delivery of various anticancer agents of synthetic and natural product origin: a patent overview, Pharmaceutical Patent Analyst, 9, 3, 2020. Crossref

  14. Raikwar Sarjana, Jain Ankit, Saraf Shivani, Bidla Pooja Das, Panda Pritish Kumar, Tiwari Ankita, Verma Amit, Jain Sanjay K., Opportunities in combinational chemo-immunotherapy for breast cancer using nanotechnology: an emerging landscape, Expert Opinion on Drug Delivery, 19, 3, 2022. Crossref

  15. Verma Amit, Tiwari Ankita, Saraf Shivani, Panda Pritish Kumar, Jain Ankit, Jain Sanjay K., Protein and peptide delivery by chitosan systems, in Chitosan in Biomedical Applications, 2022. Crossref

  16. Raikwar Sarjana, Panda Pritish Kumar, Das Bidla Pooja, Saraf Shivani, Jain Ankit, Jain Sanjay K., Liposomal Delivery System, in Nanotechnology for Biomedical Applications, 2022. Crossref

  17. Fan Xiaoxuan, Lin Xinting, Ruan Qingyan, Wang Jingyi, Yang Yinkai, Sheng Miaomiao, Zhou Wei, Kai Guoyin, Hao Xiaolong, Research progress on the biosynthesis and metabolic engineering of the anti-cancer drug camptothecin in Camptotheca acuminate, Industrial Crops and Products, 186, 2022. Crossref

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