ライブラリ登録: Guest
Begell Digital Portal Begellデジタルライブラリー 電子書籍 ジャーナル 参考文献と会報 リサーチ集
Critical Reviews™ in Eukaryotic Gene Expression
インパクトファクター: 1.841 5年インパクトファクター: 1.927 SJR: 0.649 SNIP: 0.516 CiteScore™: 1.96

ISSN 印刷: 1045-4403
ISSN オンライン: 2162-6502

Critical Reviews™ in Eukaryotic Gene Expression

DOI: 10.1615/CritRevEukarGeneExpr.v11.i1-3.90
26 pages

Critical Aspects of Tissue-Engineered Therapy for Bone Regeneration

Bruce Doll
Bone Tissue Engineering Center, Carnegie Mellon University, Pittsburgh, PA
Charles Sfeir
Bone Tissue Engineering Center, Carnegie Mellon University, Pittsburgh, PA
Shelly R. Winn
Department of Surgery, Oregon Health Sciences University, 3181 S.W. Sam Jackson Park Road, Portland OR 97201
John Huard
Bone Tissue Engineering Center, Carnegie Mellon University, Pittsburgh, PA
Jeffrey Hollinger
Bone Tissue Engineering Center, Carnegie Mellon University, Pittsburgh, PA

要約

Recent advances in bone tissue engineering are established on the understanding of an engineered scaffold, the molecular milieu within the osteogenic site, and the cell(s) predisposed to an osteogenic lineage. Advances in the incorporation of a generative vehicle into a skeletal defect require temporal and spatial distribution of the scaffold, growth factor, and cell compatible with enhanced bone healing. Monitoring events culminating in osteogenesis has focused on phenotypic and intracellular indicators. Phenotypic and intracellular indicators include the presence of receptors and intracellular signals that enable cell proliferation and differentiation. Progress in the areas of scaffold design, growth factor utilization, bone cell lineage, and intracellular signaling are reviewed.


Articles with similar content:

Regulatory Controls for Osteoblast Growth and Differentiation: Role of Runx/Cbfa/AML Factors
Critical Reviews™ in Eukaryotic Gene Expression, Vol.14, 2004, issue 1&2
Sayyed Kaleem Zaidi, Janet L. Stein, Jane B. Lian, Martin Montecino, Andre J. van Wijnen, Amjad Javed, Gary S. Stein, Christopher Lengner
Signaling Networks that Control the Lineage Commitment and Differentiation of Bone Cells
Critical Reviews™ in Eukaryotic Gene Expression, Vol.19, 2009, issue 1
Shuying Yang, Wei Chen, Carrie S. Soltanoff, Yi-Ping Li
Control of Osteoclast Differentiation
Critical Reviews™ in Eukaryotic Gene Expression, Vol.8, 1998, issue 1
G. David Roodman, Sakamuri V. Reddy
Mechanical Signaling for Bone Modeling and Remodeling
Critical Reviews™ in Eukaryotic Gene Expression, Vol.19, 2009, issue 4
Alexander G. Robling, Charles H. Turner
The Cellular and Clinical Parameters of Anabolic Therapy for Osteoporosis
Critical Reviews™ in Eukaryotic Gene Expression, Vol.13, 2003, issue 1
Clifford J. Rosen