ライブラリ登録: Guest
Begell Digital Portal Begellデジタルライブラリー 電子書籍 ジャーナル 参考文献と会報 リサーチ集
Critical Reviews™ in Eukaryotic Gene Expression
インパクトファクター: 1.841 5年インパクトファクター: 1.927 SJR: 0.649 SNIP: 0.516 CiteScore™: 1.96

ISSN 印刷: 1045-4403
ISSN オンライン: 2162-6502

Critical Reviews™ in Eukaryotic Gene Expression

DOI: 10.1615/CritRevEukarGeneExpr.v8.i1.40
pages 81-106

Regulatory Parameters of DNA Replication

Maria Zannis-Hadjopoulos
McGill Cancer Centre, McGill University, 3655 Drummond Street, Montreal, Quebec H3G 1Y6, CANADA
Gerald B. Price
McGill Cancer Centre, McGill University, 3655 Drummond Street, Montreal, Quebec H3G 1Y6, CANADA

要約

One of the fundamental characteristics that help define life is the ability to propagate. At the basest level in the act of propagation is replication of the genetic information as the databank and architectural plans for each particular life form. Thus propagation of life requires the replication of the genome−for the purposes of our review, eukaryotic DNA replication. In this critical review, we have chosen to present the issues and supporting experimental evidence in question-and-answer format. Over the past 3 to 4 years, the research domain of eukaryotic DNA replication has developed a new dynamism. This new force in discovery of the fundamental elements and mechanisms for DNA replication in higher eukaryotes has been propelled by accepted methodologies for mapping (identification) of origins of DNA replication, applicable to mammalian DNA replication, and by the discovery of the origin recognition complex (ORC) in yeast, which has served as a model in the search for the mammalian equivalent.


Articles with similar content:

A Multilingual Programming Model for Coupled Systems
International Journal for Multiscale Computational Engineering, Vol.6, 2008, issue 1
J. Walter Larson, B. Norris, E. T. Ong, R. L. Jacob, M. Steder, M. Tobis
Myc Protein: Partners and Antagonists
Critical Reviews™ in Oncogenesis, Vol.5, 1994, issue 1
Juha Klefstrom, Kari Alitalo, Tomi P. Makela, Imre Vastrik, Paivi J. Koskinen
Admittance of Slots With Coordinate Boundaries in a Half-Infinite Rectangular Waveguide With Impedance Endface
Telecommunications and Radio Engineering, Vol.52, 1998, issue 9
Yu. M. Penkin
Complementarity Relationships in Encoding Bases Along One Chain in DNA Chromosomes
Journal of Automation and Information Sciences, Vol.37, 2005, issue 8
Alexandra A. Vagis
Human TCR as Antigen: Homologies and Potentially Cross-Reactive HLA-DR2-Restricted Epitopes Within the AV and BV CDR2 Loops
Critical Reviews™ in Immunology, Vol.20, 2000, issue 1
Arthur A. Vandenbark, Halina Offner, Abigail Buenafe, David Barnes, Gregory G. Burrows, Sandra Law, Yuan K. Chou, Tom Finn, Nicole Culbertson