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International Journal of Physiology and Pathophysiology
SJR: 0.116

ISSN 印刷: 2155-014X
ISSN オンライン: 2155-0158

Archives: Volume 1, 2010 to Volume 9, 2018

International Journal of Physiology and Pathophysiology

DOI: 10.1615/IntJPhysPathophys.v2.i4.90
pages 371-377

Comparative Characteristics of Energy Supply Disturbances in Arterial and Venous Walls of Rabbits with Alloxan-Induced Diabetes and Monoiodacetate-Induced Intoxication

Oleksandr V. Ataman
Sumy State University, Sumy, Ukraine
Juriy A. Ataman
Sumy State University, Sumy, Ukraine

要約

We have shown disturbances in energy supply of the walls of the thoracic aorta and posterior vena cava of rabbits after 3 weeks from starting alloxan-induced diabetes and monoiodacetate-induced intoxication manifested as a reduction of glucose uptake and oxygen consumption, lactic acid production and re-synthesis of adenosine triphosphate (ATP) in the preparations of studied vessels. At the same time, the ATP content significantly reduced in the tissues of the arteries and veins. The possible significance of such disturbances in the development of Monckeberg’s sclerosis is discussed.


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