ライブラリ登録: Guest
Begell Digital Portal Begellデジタルライブラリー 電子書籍 ジャーナル 参考文献と会報 リサーチ集
International Journal of Medicinal Mushrooms
インパクトファクター: 1.423 5年インパクトファクター: 1.525 SJR: 0.431 SNIP: 0.716 CiteScore™: 2.6

ISSN 印刷: 1521-9437
ISSN オンライン: 1940-4344

巻:
巻 22, 2020 巻 21, 2019 巻 20, 2018 巻 19, 2017 巻 18, 2016 巻 17, 2015 巻 16, 2014 巻 15, 2013 巻 14, 2012 巻 13, 2011 巻 12, 2010 巻 11, 2009 巻 10, 2008 巻 9, 2007 巻 8, 2006 巻 7, 2005 巻 6, 2004 巻 5, 2003 巻 4, 2002 巻 3, 2001 巻 2, 2000 巻 1, 1999

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushr.v6.i4.20
12 pages

Antitumor and Immunomodulatory Effects of Culinary-Medicinal Shiitake Mushroom Lentinus edodes (Berk.) Singer: Analysis of NK Activity, Lymphoproliferative Response, and Antibody Production

Ramon Kaneno
Department of Microbiology and Immunology, Institute of Bioscience of Botucatu/UNESP, P.O. Box 510, ZC 18618-000, Botucatu, SP, Brazil
Andrea V. F. Belik
Department of Microbiology and Immunology, Institute of Bioscience of Botucatu/UNESP, Botucatu, SP, Brazil
Fabiani G. Frantz
Department of Microbiology and Immunology, Institute of Bioscience of Botucatu/UNESP, Botucatu, SP, Brazil
Juliana S. F. Lorenzo
Department of Microbiology and Immunology, Institute of Bioscience of Botucatu/UNESP, Botucatu, SP, Brazil
Luciana M. Fontanari
Department of Microbiology and Immunology, Institute of Bioscience of Botucatu/UNESP, Botucatu, SP, Brazil
Lindsey Castoldi
Department of Microbiology and Immunology, Institute of Bioscience of Botucatu/UNESP, Botucatu, SP, Brazil
Bianca R. Dias
Department of Microbiology and Immunology, Institute of Bioscience of Botucatu/UNESP, Botucatu, SP, Brazil
Ana L. T. Spinardi Barbisan
Department of Pathology, Faculty of Medicine of Botucatu/UNESP, Botucatu, SP, Brazil
Augusto Ferreira da Eira
Department of Plant Production, Agriculture Microbiology, FCA/UNESP, Botucatu, SP, Brazil

要約

We evaluated the efficiency of 12 aqueous extracts obtained at three different temperatures from four strains of culinary−medicinal Shiitake mushroom Lentinus edodes in protecting mice against the development of Ehrlich carcinoma. We observed first that the strains Le 96/17 and Le 95/ 01 of L. edodes were more efficient than JAB/k and Le 96/22 in increasing the survival time of tumor-bearing mice and that the temperature of 60 °C for extraction was more efficient than 22 °C or 100 °C for the first two strains. Groups of animals were then sacrificed following the treatments with the extract from Le 96/17 or Le 95/01 obtained at 60 °C and evaluated on the NK activity, the lymphoproliferative responsiveness of spleen cells to concanavalin A, and the specific antibody production. NK activity and proliferative response were not affected by the treatments, whereas the antitumor antibody response was enhanced by Le 95/01. Further analysis demonstrated that the extracts in vitro inhibited the NK activity and the proliferative responsiveness to concanavalin A.


Articles with similar content:

In Vitro and In Vivo Inhibition of Helicobacter pylori by Ethanolic Extracts of Lion's Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes)
International Journal of Medicinal Mushrooms, Vol.21, 2019, issue 1
Xiumin Zhang, Liping Zhang, Robert J. Maier, Ge Wang, Susan E. Maier
Immunomodulating and Antiprotozoal Effects of Different Extracts of the Oyster Culinary-Medicinal Mushroom Pleurotus ostreatus (Higher Basidiomycetes) Against Coccidiosis in Broiler
International Journal of Medicinal Mushrooms, Vol.17, 2015, issue 3
Zafar Iqbal, Masood Akhtar, Muhammad Shahid, Muhammad Irfan Ullah, Mian Muhammad Awais
Royal Sun Medicinal Mushroom, Agaricus brasiliensis (Agaricomycetidae), Derived Polysaccharides Exert Immunomodulatory Activities In Vitro and In Vivo
International Journal of Medicinal Mushrooms, Vol.18, 2016, issue 2
Weilu Wei, Lijuan Wang, Yingrui Li, Huan Zhang, Leilei Fang, Yanqing Zhang, Junbo Xie
Oral Administration of Agaricus brasiliensis S. Wasser et al. (Agaricomycetideae) Extract Downregulates Serum Immunoglobulin E Levels by Enhancing Th1 Response
International Journal of Medicinal Mushrooms, Vol.10, 2008, issue 1
Takanobu Morimoto, Michihiro Takagi, Masashi Mizuno
Combination Therapy of Transplanted Meth-A Fibrosarcoma in BALB/c Mice with Protein-Bound Polysaccharide EA6 Isolated from Enokitake Mushroom Flammulina velutipes (W.Curt.:Fr.)Singer and Surgical Excision
International Journal of Medicinal Mushrooms, Vol.7, 2005, issue 1&2
Tetsuro Ikekawa, Hirofumi Maruyama