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International Journal of Medicinal Mushrooms
インパクトファクター: 1.423 5年インパクトファクター: 1.525 SJR: 0.431 SNIP: 0.661 CiteScore™: 1.38

ISSN 印刷: 1521-9437
ISSN オンライン: 1940-4344

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushr.v14.i4.10
pages 339-345

A Concise Method Using Nuclear Magnetic Resonance Spectroscopy to Determine the Source of the β-Glucan Extracted from Various Mushrooms

Rui Tada
Laboratory for Immunopharmacology of Microbial Products, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan
Yoshiyuki Adachi
Laboratory for Immunopharmacology of Microbial Products, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan
Naohito Ohno
Tokyo University of Pharmacy and Life Sciences School of Pharmacy, Lab Immunopharmacological and Microbiological Production, 1432-1 Horinouchi, Hachioji Tokyo, 192-0392, Japan

要約

β-glucan prepared from mushrooms is used in both modern medicine and traditional oriental therapies because of its potent immunomodulatory properties. The effects of β-glucan depend on its structure and origin. Therefore, elucidating the structure and source of β-glucan is crucial for its use in food therapy and medicine. In this study, we performed NMR analysis of β-glucan preparations from various mushrooms in order to determine their structure and source. Our results show that NMR spectroscopy can be used to determine the type of mushrooms from which a β-glucan is derived on the basis of the structure of the β-glucan. We believe that this method will help promote the use of β-glucan in clinical settings and as a health food additive.