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International Journal of Medicinal Mushrooms

年間 12 号発行

ISSN 印刷: 1521-9437

ISSN オンライン: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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The Medicinal Cracked-Cap Polypore Mushroom Phellinus rimosus (Higher Basidiomycetes) Attenuates Alloxan-Induced Hyperglycemia and Oxidative Stress in Rats

巻 15, 発行 3, 2013, pp. 287-300
DOI: 10.1615/IntJMedMushr.v15.i3.60
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要約

Diabetes is usually associated with increased production of reactive oxygen species (ROS), impaired antioxidant defense systems, or both, which result in oxidative damage and lead to ROS-mediated diabetic pathogenesis. This investigation was undertaken to evaluate the role of extract from the wood-inhabiting polypore medicinal mushroom Phellinus rimosus in an alloxan-induced diabetic model and the oral glucose tolerance test in rats. Oral administration of extract at doses of 50 and 250 mg/kg body weight/day for 10 days to rats with alloxan-induced diabetes was found to possess significant dose-dependent hypoglycemic activity. In the oral glucose tolerance test, hypoglycemic effect of P. rimosus (250 mg/kg) was significant (P < 0.01) and maximum at 90 minutes after the glucose challenge when compared with that of control group. The effect of extract on antioxidant status in the pancreas, liver, and kidney was estimated. The diabetic control rats exhibited elevated levels of lipid peroxidation and lower activities of copper/zinc superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), and reduced glutathione (GSH) content in pancreatic, hepatic, and renal tissues compared with normal tissues. The activities of SOD, CAT, GPx, and GSH were found to be increased in diabetic rats treated with the extract. The increased level of lipid peroxidation in diabetic rats also was found to revert to near-normal status in groups treated with the extract. The findings thus suggest the therapeutic efficiency of Ph. Rimosus against declined antioxidant status as well as hyperglycemia associated with diabetes.

によって引用された
  1. Rony K.A., Ajith T.A., Nima N., Janardhanan K.K., Hypolipidemic activity of Phellinus rimosus against triton WR-1339 and high cholesterol diet induced hyperlipidemic rats, Environmental Toxicology and Pharmacology, 37, 2, 2014. Crossref

  2. Ganesan Kumar, Xu Baojun, Anti-Obesity Effects of Medicinal and Edible Mushrooms, Molecules, 23, 11, 2018. Crossref

  3. Dubey Sushil K., Chaturvedi Vivek K., Mishra Divya, Bajpeyee Anand, Tiwari Aprajita, Singh M. P., Role of edible mushroom as a potent therapeutics for the diabetes and obesity, 3 Biotech, 9, 12, 2019. Crossref

  4. Ehsanifard Z, Mir Mohammadrezaei F, Ghobad-Nejhad M, Safarzade AR, The Effect of Aqueous Extract of Inocutis levis on Liver Histopathology and Hypertriglyceridemia in High Sucrose-fed Wistar Rats, Journal of Medicinal Plants, 2, 70, 2019. Crossref

  5. Turło Jadwiga, The biotechnology of higher fungi - current state and perspectives, Folia Biologica et Oecologica, 10, 2014. Crossref

  6. Chen Xiaoning, Veena Ravindran Kalathil, Ramya Haridas, Janardhanan Kainoor Krishnankutty, George Varughese, Gano oil: A novel antinociceptive agent extracted from Ganoderma lucidum inhibits paw oedema and relieves pain by hypnotic and analgesic actions of fatty acid amides, Journal of Ethnopharmacology, 263, 2020. Crossref

  7. Ishara Jackson, Buzera Ariel, Mushagalusa Gustave N., Hammam Ahmed R. A., Munga Judith, Karanja Paul, Kinyuru John, Nutraceutical potential of mushroom bioactive metabolites and their food functionality, Journal of Food Biochemistry, 46, 1, 2022. Crossref

  8. Ajith Thekkuttuparambil A., Janardhanan Kainoor K., Antidiabetic Properties of Medicinal Mushrooms with Special Reference to Phellinus Species: A Review, The Natural Products Journal, 11, 2, 2021. Crossref

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