ライブラリ登録: Guest
Begell Digital Portal Begellデジタルライブラリー 電子書籍 ジャーナル 参考文献と会報 リサーチ集
International Journal of Medicinal Mushrooms
インパクトファクター: 1.423 5年インパクトファクター: 1.525 SJR: 0.431 SNIP: 0.661 CiteScore™: 1.38

ISSN 印刷: 1521-9437
ISSN オンライン: 1940-4344

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushr.v14.i1.60
pages 55-63

Yellow Brain Culinary-Medicinal Mushroom, Tremella mesenterica Ritz.:Fr. (Higher Basidiomycetes), is Subjectively but not Objectively Effective for Eradication of Helicobacter pylori: A Prospective Controlled Trial

Jesse Lachter
Faculty of Medicine and Gastroenterology: Rambam Health-Care Campus, Technion - Israel Institute of Technology
Yevgeny Yampolsky
Department of Internal Medicine C, Western Galilee Hospital University of Haifa, Mt. Carmel, Haifa, Israel.
Ronit Gafni-Schieber
Faculty of Medicine and Gastroenterology: Rambam Health-Care Campus, Technion - Israel Institute of Technology
Solomon P. Wasser
International Centre for Biotechnology and Biodiversity of Fungi Institute of Evolution and Faculty of Natural Sciences University of Haifa, Mt. Carmel, Haifa 31905, Israel

要約

Inhibitory effects of the higher Basidiomycetes mushrooms, including species of genus Tremella, on the growth of Helicobacter pyroli (Hp) have been described. This study aimed to test T. mesenterica (Tm) efficacy in vivo on eradication of Hp. This IRB-approved study included 52 consenting patients diagnosed with Hp infections. The patients were selected for 10-day treatments with one of the three arms of the protocol, namely, (i) Tm 2 g, (ii) Tm given with omeprazole 20 mg, or (iii) omeprazole 20 mg, clarithromycin 500 mg, and amoxicillin 1000 mg (all regimens given twice daily). The Tm submerged cultivated mycelium in the form of tablets (1 g) was supplied free of charge to patients. Three weeks after completing the therapy, breath testing was assessed for Hp eradication. The patients who took the standard triple therapy had a 70% (n = 14) eradication rate of Hp. Of the patients taking Tm, with and without omeprazole, only one had a breath test indicative of eradication of Hp, p < 0.000. Tm-treated patients had fewer adverse events and equivalent symptomatic relief. Limitations of this study include the brief duration of Tm therapy. Longer treatment might achieve better results, but was judged to be not warranted, so as to not excessively further delay accepted therapy. Ten-day Tm was not found to be effective in vivo in eradicating Hp, whether if given with or without omeprazole. Significant symptomatic relief found among Tm-treated patients suggests that further study of Tm is well justified.


Articles with similar content:

Antitumor Immunity in Agaricus sp., Paffia paniculata, and Propolis
International Journal of Medicinal Mushrooms, Vol.7, 2005, issue 3
Masami Oshima, Norihide Mitsumoto, Yeunhwa Gu, Toshihiro Maenaka, Takenori Yamashita, Ikukatsu Suzuki
The Effects of Phenol Nerve and Muscle Blocks in Treating Spasticity: Review of the Literature
Critical Reviews™ in Physical and Rehabilitation Medicine, Vol.8, 1996, issue 1-2
Heleen Beckerman, Gustaaf J. Lankhorst, Jules Becher, Andre L. M. Verbeek
Radioprotection by Oral Administration of Aegle marmelos (L.) Correa In Vivo
Journal of Environmental Pathology, Toxicology and Oncology, Vol.24, 2005, issue 4
Ponemone Venkatesh, Ganesh Chandra Jagetia
Electrostimulation for Refractory Epilepsy: A Review
Journal of Long-Term Effects of Medical Implants, Vol.26, 2016, issue 3
Adrian R. M. Upton, Markad V. Kamath, Hani Aodah Alzahrani, Chandrika Shenoy
Medicinal Value of Turkey Tail Fungus Trametes versicolor (L.:Fr.) Pilat (Aphyllophoromycetideae)
International Journal of Medicinal Mushrooms, Vol.7, 2005, issue 3
Christopher Hobbs