RT Journal Article
ID 1233d58a6d68bad2
A1 Rouf, Razina
A1 Tiralongo, Evelin
A1 Krahl, Anja
A1 Maes, Karen
A1 Spaan, Lina
A1 Wolf, Stefan
A1 May, Tom W.
A1 Tiralongo, Joe
T1 Comparative Study of Hemagglutination and Lectin Activity in Australian Medicinal Mushrooms (Higher Basidiomycetes)
JF International Journal of Medicinal Mushrooms
JO IJM
YR 2011
FD 2011-12-15
VO 13
IS 6
SP 493
OP 504
K1 medicinal mushrooms
K1 Australian mushrooms
K1 higher Basidiomycetes
K1 fruit-bodies
K1 hemagglutination
K1 lectin
K1 sugar specificity
AB Fifteen Australian mushroom species (higher Basidiomycetes) were assessed for hemagglutination and lectin activity. Hemagglutination activity was evaluated using both neuraminidase treated and untreated rabbit and human A, B, and O erythrocytes. Lectin activity was determined by the ability of various mono- and oligosaccharides to inhibit hemagglutination activity. Of the mushrooms evaluated, seven contained lectin activity. However, five (Agaricus bitorquis, Chlorophyllum brunneum, Coprinus comatus, Cortinarius sp. TWM 1710, and Omphalotus nidiformis) expressed lectin activity in only one of two collections tested. The two remaining lectin active mushroom species (Phlebopus marginatus and Psathyrella asperospora) possessed lectin activity with the same sugar specificity in both collections. Although lectins were identified with diverse specificity, lactose-specific lectin activity was most frequently identified, being present in Agaricus bitorquis, Copronus comatus, Omphalotus nidiformis, and Phlebopus marginatus. In contrast, Psathyrella asperospora, Cortinarius sp. TWM 1710, and Chlorophyllum brunneum were found to possess lectin activity specific for N-acetyl-D-glucosamine, galactose, and N-acetyl-neurammic acid, respectively. Significantly, the galactose-specific lectin activity identified in Cortinarius sp. TWM 1710 and the lactose-specific lectin activity in Phlebopus marginatus have not been previously reported.
PB Begell House
LK https://www.dl.begellhouse.com/journals/708ae68d64b17c52,7b5e519241ca8193,1233d58a6d68bad2.html