RT Journal Article
ID 406968853e4967fc
A1 Fatemi-Ardekani, Ali
A1 Samavati, Navid
A1 Tang, Jin
A1 Kamath, Markad
T1 Advances in Multimodality Imaging Through a Hybrid PET/MRI System
JF Critical Reviews™ in Biomedical Engineering
JO CRB
YR 2009
FD 2010-06-14
VO 37
IS 6
SP 495
OP 515
K1 magnetic resonance imaging
K1 position emission tomography
K1 computed tomography
K1 oncology
K1 molecular imaging
AB The development of integrated imaging systems for magnetic resonance imaging (MRI) and positron emission tomography (PET) is currently being explored in a number of laboratories and industrial settings. PET/MRI scanners for both preclinical and human research applications are being developed. PET/MRI overcomes many limitations of PET/computed tomography (CT), such as limited tissue contrast and high radiation doses delivered to the patient or the animal being studied. In addition, recent PET/MRI designs allow for simultaneous rather than sequential acquisition of PET and MRI data, which could not have been achieved through a combination of PET and CT scanners. In a combined PET/CT scanner, while both scanners share a common patient bed, they are hard-wired back-to-back and therefore do not allow simultaneous data acquisition. While PET/MRI offers the possibility of novel imaging strategies, it also creates considerable challenges for acquiring artifact-free images from both modalities. In this review, we discuss motivations, challenges, and potential research applications of developing PET/MRI technology. A brief overview of both MRI and PET is presented and preclinical and clinical applications of PET/MRI are identified. Finally, issues and concerns about image quality, clinical practice, and economic feasibility are discussed.
PB Begell House
LK https://www.dl.begellhouse.com/journals/4b27cbfc562e21b8,5dccbf1a4185cd3c,406968853e4967fc.html