RT Journal Article ID 4b04b3a82c949b58 A1 Dighe, Sangita A1 Agate, A. D. T1 Antibacterial Activity of Some Indian Mushrooms JF International Journal of Medicinal Mushrooms JO IJM YR 2000 FD 2000-06-01 VO 2 IS 2 OP 10 AB The antibacterial activity of 112 mushroom cultures from India was screened, and showed antibacterial activity in 18 cultures belonging to 11 genera. Good antibacterial activity of 9 species from the genera Amanita, Claudopus, Lepista, and Tricholoma was compared, and antibacterial activity was reported for the first time for Claudopus byssisedus and Amanita foetens species. Based on fast rate of growth, easy availability, cultivability, and edibility of the mushroom, in addition to a very low minimum inhibitory concentration (MIC), the strain of Lepista nuda was finally selected for further studies and was found to possess a MIC of 0.0042 μg/ml against Staphylococcus aureus and required a pH of 5.2 and temperature of 25°C for maximum production of the antibacterial substance(s). The water-soluble antibacterial substances extracted from the culture filtrate of L. nuda were found to be thermostable and acidic and were identified on the basis of ultraviolet (UV) absorption spectra as polyacetylenic compound(s). PB Begell House LK https://www.dl.begellhouse.com/journals/708ae68d64b17c52,452b39d115b42ef7,4b04b3a82c949b58.html