RT Journal Article ID 5d019a3410734254 A1 Garside , Paul A1 Mowat, Allan Mcl T1 Mechanisms of Oral Tolerance JF Critical Reviews™ in Immunology JO CRI YR 1997 FD 1997-06-30 VO 17 IS 2 SP 119 OP 137 K1 oral tolerance K1 suppression K1 anergy K1 deletion K1 T cells K1 therapy K1 cytokines K1 mucosal K1 co-stimulation. AB Oral tolerance is the specific immunological unresponsiveness induced by feeding antigen. Although it is an obstacle to oral vaccination, it is probably the mechanism that prevents intestinal hypersensitivity reactions to food antigens and may provide a novel strategy for the treatment of a range of inflammatory disorders. Feeding antigen can provide stable and long-lasting tolerance of a wide range of immune responses to a variety of antigens. However, the mechanisms of oral tolerance and the major factors that influence them remain controversial. PB Begell House LK https://www.dl.begellhouse.com/journals/2ff21abf44b19838,14d7408449cd5631,5d019a3410734254.html