RT Journal Article ID 73c1651300466386 A1 Apostolopoulos, Alexandros P. A1 Tsiotsias, Anastasios A1 Zouboulis, George A1 Karadimas, Efthymios J. A1 Pernientakis, Stylianos A1 Balfousias, Theodore A1 Papanikolaou, Athanasios T1 SEPSIS SECONDARY TO DELAYED PRESENTATION OF NECROTISING FASCIITIS OF THE THIGH—PRESENTATION OF TWO CASES WITH A POOR OUTCOME JF Journal of Long-Term Effects of Medical Implants JO JLT YR 2018 FD 2019-01-07 VO 28 IS 4 SP 309 OP 317 K1 necrotizing fasciitis K1 sepsis K1 mortality AB Necrotizing fasciitis is an extremely virulent form of infectious fasciitis. It affects skin, subcutaneous fat, and superficial and deep muscular fascia by rapidly progressive necrosis. We present two cases, a 54-year-old female patient and a 46-year-old male patient, who presented to the emergency department of our hospital 30 days and 14 days after the onset of symptoms, respectively, with progressively deteriorating pain and swelling of the thigh, accompanied by fever, nausea, sweating, shortness of breath, and sepsis. Clinical, laboratory, and imaging findings suggested thigh fasciitis, which was secondary to osteomyelitis of the femoral head in one case. Despite the urgent surgical exploration and debridement, multiple courses of various schemes of intravenous antibiotics administered, the numerous surgical debridements and interventions performed, and the prolonged hospitalization in the intensive care unit, both patients died due to multiple-organ failure and disseminated intravascular coagulation. Necrotizing fasciitis is of surgical urgency with a high mortality rate, and early surgical intervention is of vital importance. In both of these cases, delayed presentation to the hospital was of great significance to the final outcome. PB Begell House LK https://www.dl.begellhouse.com/journals/1bef42082d7a0fdf,63c116d938b8aa0e,73c1651300466386.html