RT Journal Article ID 7866e1ca64abefd9 A1 Ermolaeva, Svetlana A. A1 Petrov, Oleg F. A1 Akishev, Yuri A1 Vasilets, Viktor N. A1 Sysolyatina, Elena V. A1 Vasiliev, Mikhail M. A1 Naroditsky, Boris S. A1 Morfill, Gregor Ego A1 Grigoriev, Anatoly I. A1 Fortov, Vladimir Evgenievich A1 Gintsburg, Alexander L. T1 Comparative Study of Three Nonthermal Plasma Sources against Causative Agents of Nosocomial Infections JF Plasma Medicine JO PMED YR 2012 FD 2014-06-30 VO 2 IS 1-3 SP 141 OP 149 K1 bactericidal activity K1 nonthermal plasma K1 microwave argon plasma K1 ferroelectric plasma generator K1 positive and negative corona discharge AB Nonthermal plasmas (NTPs) represent a perspective class of antibacterial agents that might be an alternative to chemical disinfectants because they possess an unspecific antimicrobial activity and can be applied to decontamination of heat- and chemical-sensitive surfaces as well as to the infected skin and wounds. The resistance to NTP depends on properties of both a microorganism and a certain plasma source. Two bacterial species, Pseudomonas aeruginosa and Staphylococcus aureus, which are among the most important causative agents of nosocomial infections, were tested with three different plasma sources. The ferroelectric air plasma generator, the microwave argon plasma source, and the generator of a positive and negative corona discharge in air demonstrated increasing activity toward tested bacteria. The relative resistance of the tested strains to NTPs produced by distinct plasma sources differed. P. aeruginosa was more resistance to the corona discharge and less resistant to the plasma generated by the ferroelectric generator than S. aureus while both strains demonstrated comparable resistance to microwave argon plasma. Obtained results demonstrated a role of charged particles as a primary factor in the high effectiveness of the positive and negative coronas and an importance of the NO• radical among neutral active species. PB Begell House LK https://www.dl.begellhouse.com/journals/5a5b4a3d419387fb,23f772c6503d3a49,7866e1ca64abefd9.html