DOI: 10.1615/TSFP5
TOWARDS MORE EFFICIENT DRUG DELIVERY: BLOOD FLOW IN STENOTIC ARTERIES SUBJECTED TO A STRONG NON-UNIFORM MAGNETIC FIELD
要約
The paper reports on a comprehensive mathematical model for simulations of blood-flow under presence of non-uniform magnetic fields. The model consists of from set of Navier-Stokes equations extended with both Lorentz and magnetization forces including a simplified set of Maxwell's equations (Ampere's law) for predictions of imposed magnetic fields. An extensive literature survey is performed in order to find all relevant hydrodynamic and electro-magnetic properties of human blood. The model is then extensively tested for a range of test cases ranging from a simple cylindrical geometries to realistic right-coronary arteries in humans. Both, a time-dependency of the wall-shear-stress for different stenosis growth rates as well as effects of an imposed non-uniform magnetic fields on the blood flow pattern are presented and analyzed. It is concluded that an imposed non-uniform magnetic field can create significant changes in the secondary flow patterns thus making it possible to use this technique for optimized targeted drug delivery.