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Journal of Long-Term Effects of Medical Implants
SJR: 0.133 SNIP: 0.491 CiteScore™: 0.89

ISSN Imprimir: 1050-6934
ISSN On-line: 1940-4379

Journal of Long-Term Effects of Medical Implants

DOI: 10.1615/JLongTermEffMedImplants.2013010138
pages 93-104

The Natural History of Knee Osteoarthritis: India-based Knee Osteoarthritis Evaluation (iKare): A Study Protocol

Alexa Gilbert
Global Research Solutions, Inc., Burlington, Ontario, Canada
Chuan Silvia Li
Global Research Solutions, Inc., Burlington, Ontario, Canada; Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
Parag Sancheti
Sancheti Institute for Orthopaedics & Rehabilitation, Shivajinagar, Pune, Maharashtra, India
Beate Hanson
AO Foundation, AO Clinical Investigation and Documentation (AOCID), Dübendorf, Switzerland
Mandeep S. Dhillon
Department of Physical Medicine & Rehabilitation; Department of Orthopaedics, Post Graduate Institute of Medical Education and Research, Chandigarh, India
Rajeev Naik
Department of Orthopaedics, Dr. B.R. Ambedkar Medical College, Bangalore; Tamil Nadu Dr. M.G.R. Medical University, Tamil Nadu, India
Nishith V. Shah
Arthroscopy Sports Medicine, Aash Arthroscopy Centre, Opp. Jalaram Temple, Paldi, Ahmedabad, India
Vijay D. Shetty
Hiranandani Orthopaedic Medical Education, Dr. L.H. Hiranandani Hospital Hiranandani Gardens, Powai, Mumbai, India
Gurava Reddy
Sunshine Hospitals, Secunderabad, India
Jairam Jagiasi
B.Y.L. Nair Hospital & T.N. Medical College, Bombay Central, Mumbai, India
Anil Kumar Reddy
Sunshine Hospitals, Secunderabad, India
Utsav Ganguly
Sunshine Hospitals, Secunderabad, India
Neelam Jhangiani
Sancheti Institute for Orthopaedics & Rehabilitation, Shivajinagar, Pune, Maharashtra, India
Mohit Bhandari
CLARITY Research Group, McMaster University, Department of Orthopedic Surgery Musculoskeletal Research Unit, Canada and Division of Orthopaedic Surgery and Department of Clinical Epidemiology & Biostatistics, Hamilton General Hospital, Canada


Methodology: Multi-center, cross-sectional, observational study.
Study Center(s): Multiple centers in India.
Number of Participants: 1,000.
Primary Research Objective: To characterize patients and treatment utilized for orthopedic patients presenting to both private and public hospital centers in India with knee pain and symptoms suggestive of knee arthritis.
Inclusion Criteria: All patients 18 years of age or older who present to a recruiting hospital for treatment of knee pain will be eligible for participation. The subjects must be able to understand and complete the questionnaire.
Exclusion Criteria: Patients with total knee replacement, open wound or evidence of recent surgery, or with a current or a history of tumor and/or fracture in the tibial plateau, femoral condyle or patella, in the affected knee are not eligible.
Study Outcomes: This study aims to characterize the following: general demographics of patients presenting with knee pain, severity of knee symptoms at time of presentation, severity of knee pathology at time of presentation, factors associated with the decision to seek medical care, previous treatments and health care contacts, planned treatment, and gaps in treatment perceived by the patient and treating surgeons.

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