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Journal of Long-Term Effects of Medical Implants

Publicou 4 edições por ano

ISSN Imprimir: 1050-6934

ISSN On-line: 1940-4379

SJR: 0.184 SNIP: 0.485 CiteScore™:: 1.1 H-Index: 39

Indexed in

Histologic and Hemodynamic Effects of Endosaccular Platinum Coils for Intracranial Aneurysms

Volume 14, Edição 3, 2004, 18 pages
DOI: 10.1615/JLongTermEffMedImplants.v14.i3.70
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RESUMO

Over the past 15 years, endosaccular platinum coil therapy for intracranial aneurysms has evolved from clinical pilot studies of investigational devices to common clinical practice. The mechanism by which these coils reduce the risk of aneurysm rupture—the primary goal of intracranial aneurysm treatment—is the focus of this review. Both histological mechanisms of scar formation and hemodynamic mechanisms of flow diversion may be involved. We will first review aneurysm epidemiology to provide the context and rationale for therapy for patients harboring intracranial aneurysms. Next, we will review the data for and theories of the pathophysiology of aneurysm formation, growth, and rupture, particularly as they relate to endovascular coil therapy. Histological and hemodynamic studies of coiled aneurysms in animals and humans will be reviewed. Fınally, we will discuss emerging coil-based therapies, such as bioactive polymer coatings for platinum coils and the adjunctive use of stents.

CITADO POR
  1. Rivet D.J., Moran C.J., Mazumdar A., Pilgram T.K., Derdeyn C.P., Cross D.T., Single-Institution Experience with Matrix Coils in the Treatment of Intracranial Aneurysms: Comparison with Same-Center Outcomes with the Use of Platinum Coils, American Journal of Neuroradiology, 28, 9, 2007. Crossref

  2. Sherif C., Bavinzski G., Dorfer C., Kanz F., Schuster E., Plenk H., Computerized Assessment of Angiographic Occlusion Rate and Coil Density in Embolized Human Cerebral Aneurysms, American Journal of Neuroradiology, 30, 5, 2009. Crossref

  3. Valencia Alvaro, Botto Sergio, Sordo Juan, Galvez Marcelo, Badilla Lautaro, Comparison of haemodynamics in cerebral aneurysms of different sizes located in the ophthalmic artery, International Journal for Numerical Methods in Fluids, 53, 5, 2007. Crossref

  4. Valencia Alvaro, Morales Hernan, Rivera Rodrigo, Bravo Eduardo, Galvez Marcelo, Blood flow dynamics in patient-specific cerebral aneurysm models: The relationship between wall shear stress and aneurysm area index, Medical Engineering & Physics, 30, 3, 2008. Crossref

  5. Wang Qiujing, Gao Yuyuan, Sun Xinlin, Ji Bin, Cui Xubo, Liu Yaqi, Zheng Tao, Chen Chengwei, Jiang Xiaodan, Zhu Aiping, Quan Daping, Acceleration of aneurysm healing by P(DLLA-co-TMC)-coated coils enabling the controlled release of vascular endothelial growth factor, Biomedical Materials, 9, 4, 2014. Crossref

  6. Sorteberg A., Farhoudi D., The Influence of Aneurysm Configuration on Intra-Aneurysmal Pressure and Flow, Interventional Neuroradiology, 12, 3, 2006. Crossref

  7. Macdonald R. Loch, Editorial: Aneurysm wall inflammation, Journal of Neurosurgery, 120, 1, 2014. Crossref

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