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Critical Reviews™ in Immunology

Publicou 6 edições por ano

ISSN Imprimir: 1040-8401

ISSN On-line: 2162-6472

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.3 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.6 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00079 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.24 SJR: 0.429 SNIP: 0.287 CiteScore™:: 2.7 H-Index: 81

Indexed in

Role of CD3ε-Mediated Signaling in T-Cell Development and Function

Volume 31, Edição 1, 2011, pp. 73-84
DOI: 10.1615/CritRevImmunol.v31.i1.70
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RESUMO

Receptor-mediated signal transduction plays an important role in T-cell differentiation and function. The pre-T-cell receptor (pre-TCR) and TCR complexes are the most critical receptors for T-cell biology. Signals induced by pre-TCR and TCR in a ligand-independent or a ligand-dependent manner, respectively, are essential for thymocyte maturation. CD3 proteins, which are γ, δ, ε, and ζ polypeptides, play pivotal role in intracellular assembly, surface expression, and signal transduction via the pre-TCR and TCR complexes. Recent studies have suggested central and multiple roles for CD3ε in T-cell development and function. We review the role of the CD3ε chain in T-cell biology.

Palavras-chave: pre-TCR, TCR, CD3, T-cell development
CITADO POR
  1. Li Bo, Niu Yuzhe, Liu Sichu, Yu Wei, Chen Jiayu, Wu Lin, Liu Weiwei, Chen Shaohua, Yang Lijian, Li Yangqiu, A change in CD3γ, CD3δ, CD3ϵ, and CD3ζgene expression in T-lymphocytes from benzene-exposed and benzene-poisoned workers, Journal of Immunotoxicology, 9, 2, 2012. Crossref

  2. Luan Rong, Cheng Hao, Li Lin, Zhao Qiang, Liu Hui, Wu Zhenzhou, Zhao Liqing, Yang Jinghua, Hao Jianlei, Yin Zhinan, Maternal Lipopolysaccharide Exposure Promotes Immunological Functional Changes in Adult Offspring CD4+T Cells, American Journal of Reproductive Immunology, 73, 6, 2015. Crossref

  3. Mitra Soma, Sinha Ritam, Mitobe Jiro, Koley Hemanta, Development of a cost-effective vaccine candidate with outer membrane vesicles of a tolA-disrupted Shigella boydii strain, Vaccine, 34, 15, 2016. Crossref

  4. Mircheff Austin K., Wang Yanru, Li Meng, Pan Billy X., Ding Chuanqing, Pregnancy probabilistically augments potential precursors to chronic, immune-mediated or autoimmune lacrimal gland infiltrates, The Ocular Surface, 16, 1, 2018. Crossref

  5. Zhu Xinxin, Lang Jinghe, Programmed death-1 pathway blockade produces a synergistic antitumor effect: combined application in ovarian cancer, Journal of Gynecologic Oncology, 28, 5, 2017. Crossref

  6. Miyazawa Ryuichiro, Murata Norifumi, Matsuura Yuta, Shibasaki Yasuhiro, Yabu Takeshi, Nakanishi Teruyuki, Peculiar Expression of CD3-Epsilon in Kidney of Ginbuna Crucian Carp, Frontiers in Immunology, 9, 2018. Crossref

  7. Gaffney Stephen G., Perry Elizabeth B., Chen Ping-Min, Greenstein Andrew, Kaech Susan M., Townsend Jeffrey P., The landscape of novel and complementary targets for immunotherapy: an analysis of gene expression in the tumor microenvironment, Oncotarget, 10, 44, 2019. Crossref

  8. Alewine Christine, Hassan Raffit, Pastan Ira, Advances in Anticancer Immunotoxin Therapy, The Oncologist, 20, 2, 2015. Crossref

  9. Chen Changjun, Zhao Xin, Luo Yue, Li Bohua, Li Qianhao, Zhao Chengcheng, Huang Yan, Kang Pengde, Imbalanced T-Cell Subsets May Facilitate the Occurrence of Osteonecrosis of the Femoral Head, Journal of Inflammation Research, Volume 15, 2022. Crossref

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