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Critical Reviews™ in Oncogenesis
SJR: 0.631 SNIP: 0.503 CiteScore™: 2.2

ISSN Imprimir: 0893-9675
ISSN On-line: 2162-6448

Critical Reviews™ in Oncogenesis

DOI: 10.1615/CritRevOncog.2013007889
pages 471-483

Iron, Erythropoietic Stimulating Agents, and Anemia in Cancer

John W. Adamson
Clinical Professor of Medicine, University of California, VA San Diego Healthcare System MC 111E 3350 La Jolla Village Drive, San Diego, CA 92161


Anemia commonly accompanies malignancies in patients and may contribute to morbidity. Correction of the anemia with erythropoietic stimulating agents, while possible, may be associated with complications such as tumor progression and adverse cardiovascular events. This review examines the data behind these concerns and raises the strategy of using iron, alone, in the setting of cancer-associated anemia to reduce exposure to transfusions in these patients and to potentially improve their quality of life.

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