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Critical Reviews™ in Biomedical Engineering
SJR: 0.26 SNIP: 0.375 CiteScore™: 1.4

ISSN Imprimir: 0278-940X
ISSN On-line: 1943-619X

Volumes:
Volume 48, 2020 Volume 47, 2019 Volume 46, 2018 Volume 45, 2017 Volume 44, 2016 Volume 43, 2015 Volume 42, 2014 Volume 41, 2013 Volume 40, 2012 Volume 39, 2011 Volume 38, 2010 Volume 37, 2009 Volume 36, 2008 Volume 35, 2007 Volume 34, 2006 Volume 33, 2005 Volume 32, 2004 Volume 31, 2003 Volume 30, 2002 Volume 29, 2001 Volume 28, 2000 Volume 27, 1999 Volume 26, 1998 Volume 25, 1997 Volume 24, 1996 Volume 23, 1995

Critical Reviews™ in Biomedical Engineering

DOI: 10.1615/CritRevBiomedEng.v38.i1.50
pages 53-63

Biophysics of Radiofrequency Ablation

Dieter Haemmerich
Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina, USA; Department of Bioengineering, Clemson University, Clemson, South Carolina, USA

RESUMO

Radiofrequency (RF) ablation is a treatment modality that kills unwanted tissue by heat. Starting with cardiac arrhythmia treatment in the 1980s, RF ablation has found clinical application in a number of diseases, and is now the treatment of choice for certain types of cardiac arrhythmia and certain cancers. During RF ablation, an electrode is inserted into or steered intravascularly to the target tissue region under medical imaging guidance. Then, a tissue volume surrounding the electrode is destroyed by heating via RF electric current. This paper reviews the biophysics of tissue heating during RF ablation. Effects of electrical tissue conductivity and its change with temperature are discussed. Procedures and devices specific for cancer treatment and for arrhythmia treatment are presented with a brief discussion of additional clinical applications.


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