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Critical Reviews™ in Eukaryotic Gene Expression

Publicou 6 edições por ano

ISSN Imprimir: 1045-4403

ISSN On-line: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

Indexed in

Linkage of Lamins to Fidelity of Gene Transcription

Volume 15, Edição 4, 2005, pp. 277-294
DOI: 10.1615/CritRevEukarGeneExpr.v15.i4.10
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RESUMO

Two major events are emerging as being involved in the fine regulatory mechanisms that control gene expression through the nuclear envelope/lamina. The first is the linkage of envelope proteins to transcription factors, most of which function as transcriptional repressors. The second is the interplay between nuclear lamina/nuclear envelope proteins and chromatin, through more or less direct interactions with DNA-binding proteins. The first mechanism appears to play a major role in tissue-specific functions, whereas the latter mechanism likely modifies higher-order chromatin organization, thus regulating differentiation and aging. This review highlights the importance of the study of a group of genetic diseases, collectively referred to as laminopathies, to understand the actual role played by lamins in ensuring the fidelity of gene expression and in modulating cеll differentiation.

CITADO POR
  1. Maraldi Nadir M., Lattanzi Giovanna, Cenni Vittoria, Bavelloni Alberto, Marmiroli Sandra, Manzoli Francesco A., Laminopathies and A-type lamin-associated signalling pathways, Advances in Enzyme Regulation, 50, 1, 2010. Crossref

  2. Marmiroli Sandra, Bertacchini Jessika, Beretti Francesca, Cenni Vittoria, Guida Marianna, De Pol Anto, Maraldi Nadir M., Lattanzi Giovanna, A-type lamins and signaling: The PI 3-kinase/Akt pathway moves forward, Journal of Cellular Physiology, 220, 3, 2009. Crossref

  3. Maraldi Nadir M., Capanni Cristina, Lattanzi Giovanna, Camozzi Daria, Facchini Andrea, Manzoli Francesco A., SREBP1 interaction with prelamin A forms: A pathogenic mechanism for lipodystrophic laminopathies, Advances in Enzyme Regulation, 48, 1, 2008. Crossref

  4. Maraldi Nadir M., Lattanzi Giovanna, Laminopathies, in Cytoskeleton and Human Disease, 2012. Crossref

  5. Maraldi Nadir M., A Lipid-based Code in Nuclear Signalling, in The Codes of Life, 1, 2008. Crossref

  6. Boschmann Michael, Engeli Stefan, Moro Cedric, Luedtke Angelika, Adams Frauke, Gorzelniak Kerstin, Rahn Gabriele, Mähler Anja, Dobberstein Kerstin, Krüger Antje, Schmidt Saskia, Spuler Simone, Luft Friedrich C., Smith Steven R., Schmidt Hartmut H.-J., Jordan Jens, LMNA Mutations, Skeletal Muscle Lipid Metabolism, and Insulin Resistance, The Journal of Clinical Endocrinology & Metabolism, 95, 4, 2010. Crossref

  7. Lattanzi Giovanna, Prelamin A-mediated nuclear envelope dynamics in normal and laminopathic cells, Biochemical Society Transactions, 39, 6, 2011. Crossref

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