Inscrição na biblioteca: Guest
Critical Reviews™ in Eukaryotic Gene Expression

Publicou 6 edições por ano

ISSN Imprimir: 1045-4403

ISSN On-line: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

Indexed in

Inside the Mammalian Telomere Interactome: Regulation and Regulatory Activities of Telomeres

Volume 16, Edição 2, 2006, pp. 103-118
DOI: 10.1615/CritRevEukarGeneExpr.v16.i2.10
Get accessGet access

RESUMO

Work in model organisms, such as mouse, yeast, Tetrahymena, ciliates, and plants, has led to a deeper understanding of telomere biology. Telomeres together with telomere-binding proteins have evolved to protect chromosomal ends and maintain chromosomal length and integrity. Over the last two decades, biochemical, molecular, cellular, and genetic studies have greatly enhanced our knowledge of the unique function and structure of telomeres and telomere-associated factors. In this review, we focus on the important advances, in terms of our knowledge and the methods used, in understanding mammalian telomere regulation by telomeric proteins. Recently, the 6 telomeric proteins ( TRF1, TRF2, POT1, TIN2, RAP1, and TPP1) were found to form a high-order complex. This complex and its associated partners provide the basis for constructing an interaction map of telomere regulators in mammalian cells, which we named the Telomere Interactome. The Telomere Interactome incorporates the various telomere signaling pathways and represents the molecular machinery that regulates mammalian telomeres. The establishment of the Telomere Interactome will also enable the integration of the intricate circuitries that regulate telomeres with other cellular interactomes in vertebrates.

CITADO POR
  1. Xin Huawei, Liu Dan, Wan Ma, Safari Amin, Kim Hyeung, Sun Wen, O’Connor Matthew S., Songyang Zhou, TPP1 is a homologue of ciliate TEBP-β and interacts with POT1 to recruit telomerase, Nature, 445, 7127, 2007. Crossref

  2. Kim Hyeung, Lee Ok-Hee, Xin Huawei, Chen Liuh-Yow, Qin Jun, Chae Heekyung Kate, Lin Shiaw-Yih, Safari Amin, Liu Dan, Songyang Zhou, TRF2 functions as a protein hub and regulates telomere maintenance by recognizing specific peptide motifs, Nature Structural & Molecular Biology, 16, 4, 2009. Crossref

  3. Lin Jiangguo, Kaur Parminder, Countryman Preston, Opresko Patricia L., Wang Hong, Unraveling secrets of telomeres: One molecule at a time, DNA Repair, 20, 2014. Crossref

  4. Zhang Sijie, Luo Zhenhua, Shi Guang, Liu Dan, Songyang Zhou, Huang Junjiu, TPP1 as a versatile player at the ends of chromosomes, Frontiers in Biology, 9, 3, 2014. Crossref

  5. Aubert Geraldine, Telomere Dynamics and Aging, in Telomeres in Health and Disease, 125, 2014. Crossref

  6. Rajavel Malligarjunan, Mullins Michael R., Taylor Derek J., Multiple facets of TPP1 in telomere maintenance, Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1844, 9, 2014. Crossref

  7. Zhu Qubo, Meng Lingjun, Hsu Joseph K., Lin Tao, Teishima Jun, Tsai Robert Y.L., GNL3L stabilizes the TRF1 complex and promotes mitotic transition, Journal of Cell Biology, 185, 5, 2009. Crossref

  8. Hsu Joseph K., Lin Tao, Tsai Robert Y.L., Nucleostemin prevents telomere damage by promoting PML-IV recruitment to SUMOylated TRF1, Journal of Cell Biology, 197, 5, 2012. Crossref

  9. Croy Johnny E., Wuttke Deborah S., Themes in ssDNA recognition by telomere-end protection proteins, Trends in Biochemical Sciences, 31, 9, 2006. Crossref

  10. Grandin Nathalie, Charbonneau Michel, Protection against chromosome degradation at the telomeres, Biochimie, 90, 1, 2008. Crossref

  11. Luo Z., Dai Z., Xie X., Feng X., Liu D., Songyang Z., Xiong Y., TeloPIN: a database of telomeric proteins interaction network in mammalian cells, Database, 2015, 2015. Crossref

  12. Moores Carly J., Fenech Michael, O’Callaghan Nathan J., Telomere dynamics: the influence of folate and DNA methylation, Annals of the New York Academy of Sciences, 1229, 1, 2011. Crossref

  13. Kaur Parminder, Wu Dong, Lin Jiangguo, Countryman Preston, Bradford Kira C., Erie Dorothy A., Riehn Robert, Opresko Patricia L., Wang Hong, Enhanced electrostatic force microscopy reveals higher-order DNA looping mediated by the telomeric protein TRF2, Scientific Reports, 6, 1, 2016. Crossref

  14. Lin Jiangguo, Countryman Preston, Chen Haijiang, Pan Hai, Fan Yanlin, Jiang Yunyun, Kaur Parminder, Miao Wang, Gurgel Gisele, You Changjiang, Piehler Jacob, Kad Neil M., Riehn Robert, Opresko Patricia L., Smith Susan, Tao Yizhi Jane, Wang Hong, Functional interplay between SA1 and TRF1 in telomeric DNA binding and DNA–DNA pairing, Nucleic Acids Research, 44, 13, 2016. Crossref

  15. Gaullier Guillaume, Miron Simona, Pisano Sabrina, Buisson Rémi, Le Bihan Yann-Vaï, Tellier-Lebègue Carine, Messaoud Wala, Roblin Pierre, Guimarães Beatriz G., Thai Robert, Giraud-Panis Marie-Josèphe, Gilson Eric, Le Du Marie-Hélène, A higher-order entity formed by the flexible assembly of RAP1 with TRF2, Nucleic Acids Research, 44, 4, 2016. Crossref

  16. Songyang Zhou, Introduction to Telomeres and Telomerase, in Telomeres and Telomerase, 1587, 2017. Crossref

  17. Aubert Geraldine, Lansdorp Peter M., Telomeres and Aging, Physiological Reviews, 88, 2, 2008. Crossref

  18. Beck Jennifer L., Developments in Electrospray Ionization Mass Spectrometry of Non-Covalent DNA–Ligand Complexes, Australian Journal of Chemistry, 64, 6, 2011. Crossref

  19. Liu Feng, Feng Xuyang, Ma Wenbin, Analysis of Telomere Proteins by Chromatin Immunoprecipitation (ChIP), in Telomeres and Telomerase, 1587, 2017. Crossref

  20. Ma Wenbin, Lee Ok-hee, Kim Hyeung, Songyang Zhou, Using Protein-Fragment Complementation Assays (PCA) and Peptide Arrays to Study Telomeric Protein-Protein Interactions, in Telomeres and Telomerase, 1587, 2017. Crossref

  21. Lee Ok-Hee, Kim Hyeung, He Quanyuan, Baek Hwa Jin, Yang Dong, Chen Liuh-Yow, Liang Jiancong, Chae Heekyung Kate, Safari Amin, Liu Dan, Songyang Zhou, Genome-wide YFP Fluorescence Complementation Screen Identifies New Regulators for Telomere Signaling in Human Cells, Molecular & Cellular Proteomics, 10, 2, 2011. Crossref

  22. Saretzki Gabriele, Telomeres, Telomerase and Ageing, in Biochemistry and Cell Biology of Ageing: Part I Biomedical Science, 90, 2018. Crossref

  23. Londoño-Vallejo J. Arturo, Telomeres, Epigenetics, and Aging, in Epigenetics of Aging, 2010. Crossref

  24. Petreaca Ruben C, Chiu Huan-Chih, Nugent Constance I, The Role of Stn1p in Saccharomyces cerevisiae Telomere Capping Can Be Separated From Its Interaction With Cdc13p, Genetics, 177, 3, 2007. Crossref

  25. Songyang Zhou, Introduction to Telomeres and Telomerase, in Telomeres and Telomerase, 735, 2011. Crossref

  26. Ma Wenbin, Analysis of Telomere Proteins by Chromatin Immunoprecipitation (ChIP), in Telomeres and Telomerase, 735, 2011. Crossref

  27. Ma Wenbin, Kim Hyeung, Songyang Zhou, Studying of Telomeric Protein–Protein Interactions by Bi-Molecular Fluorescence Complementation (BiFC) and Peptide Array-Based Assays, in Telomeres and Telomerase, 735, 2011. Crossref

  28. Menendez Javier A., Benboudjema Louisa, Vellon Luciano, Rubio Miguel A., Espinoza Ingrid, Campisi Judith, Lupu Ruth, Heregulin, a new interactor of the telosome/shelterin complex in human telomeres, Oncotarget, 6, 37, 2015. Crossref

  29. Li Hai-Long, Song Jun, Yong Hong-Mei, Hou Ping-Fu, Chen Yan-Su, Song Wen-Bo, Bai Jin, Zheng Jun-Nian, PinX1: structure, regulation and its functions in cancer, Oncotarget, 7, 40, 2016. Crossref

  30. Meng Lingjun, Hsu Joseph K., Zhu Qubo, Lin Tao, Tsai Robert Y. L., Nucleostemin inhibits TRF1 dimerization and shortens its dynamic association with the telomere, Journal of Cell Science, 124, 21, 2011. Crossref

  31. Pan Hai, Kaur Parminder, Barnes Ryan, Detwiler Ariana C., Sanford Samantha Lynn, Liu Ming, Xu Pengning, Mahn Chelsea, Tang Qingyu, Hao Pengyu, Bhattaram Dhruv, You Changjiang, Gu Xinyun, Lu Warren, Piehler Jacob, Xu Guozhou, Weninger Keith, Riehn Robert, Opresko Patricia L., Wang Hong, Structure, dynamics, and regulation of TRF1-TIN2-mediated trans- and cis-interactions on telomeric DNA, Journal of Biological Chemistry, 297, 3, 2021. Crossref

  32. Parks Joseph W., Stone Michael D., Single-Molecule Studies of Telomeres and Telomerase, Annual Review of Biophysics, 46, 1, 2017. Crossref

  33. Kaur Parminder, Barnes Ryan, Pan Hai, Detwiler Ariana C, Liu Ming, Mahn Chelsea, Hall Jonathan, Messenger Zach, You Changjiang, Piehler Jacob, Smart Robert C, Riehn Robert, Opresko Patricia L, Wang Hong, TIN2 is an architectural protein that facilitates TRF2-mediated trans- and cis-interactions on telomeric DNA, Nucleic Acids Research, 49, 22, 2021. Crossref

  34. Chen Liuh-Yow, Liu Dan, Songyang Zhou, Telomere Maintenance through Spatial Control of Telomeric Proteins, Molecular and Cellular Biology, 27, 16, 2007. Crossref

  35. Wan Ma, Qin Jun, Songyang Zhou, Liu Dan, OB Fold-containing Protein 1 (OBFC1), a Human Homolog of Yeast Stn1, Associates with TPP1 and Is Implicated in Telomere Length Regulation, Journal of Biological Chemistry, 284, 39, 2009. Crossref

  36. O'Connor Matthew S., Safari Amin, Xin Huawei, Liu Dan, Songyang Zhou, A critical role for TPP1 and TIN2 interaction in high-order telomeric complex assembly, Proceedings of the National Academy of Sciences, 103, 32, 2006. Crossref

  37. Robles-Espinoza Carla Daniela, del Castillo Velasco-Herrera Martin, Hayward Nicholas K., Adams David J., Telomere-Regulating Genes and the Telomere Interactome in Familial Cancers, Molecular Cancer Research, 13, 2, 2015. Crossref

  38. Kim Hyeung, Li Feng, He Quanyuan, Deng Tingting, Xu Jun, Jin Feng, Coarfa Cristian, Putluri Nagireddy, Liu Dan, Songyang Zhou, Systematic analysis of human telomeric dysfunction using inducible telosome/shelterin CRISPR/Cas9 knockout cells, Cell Discovery, 3, 1, 2017. Crossref

Próximos artigos

PRMT6 promotes the immune evasion of gastric cancer via upregulating ANXA1 Liang Xu, Fenger Zhang, Binqi Yu, Shengnan Jia, Sunfu Fan PURPL promotes M2 macrophage polarization in lung cancer via regulating RBM4/xCT signaling Jipeng Guo, Chongwen Gong, Hao Wang SIAH1 promotes the pyroptosis of cardiomyocytes in diabetic cardiomyopathy via regulating IκB-α/NF-κB signaling Jinbin Wu, Yaoming Yan SLC7A2-mediated lysine catabolism inhibits immunosuppression in triple negative breast cancer Yuanyuan Sun, Yaqing Li, Chengying Jiang, Chenying Liu, Yuanming Song SIAH2-mediated degradation of ACSL4 inhibits the anti-tumor activity of CD8+ T cells in hepatocellular carcinoma Fangzheng Shu, Yuhua Shi, Xiangxiang Shan, Wenzhang Zha, Rengen Fan, Wanjiang Xue RBM15-mediated N6-methyl adenosine (m6A) modification of EZH2 drives the epithelial-mesenchymal transition of cervical cancer Ruixue Wang, Wenhua Tan Evidence-Based Storytelling and A Strategic Roadmap to Promote Cancer Prevention Via Adolescent HPV Vaccination in Northern New England Matthew Dugan, Gary Stein, Jan Carney, Sheila Clifford-Bova KDM4A-AS1 promotes cell proliferation, migration and invasion via the miR-4306/STX6 axis in hepatocellular carcinoma Wei Cao, Yuhan Ren, Ying Liu, Guoshu Cao, Zhen Chen, Fan Wang HDAC1-mediated downregulation of NEU1 exacerbates the aggressiveness of cervical cancer Nanzi Xie, Sisi Mei, Changlan Dai, Wei Chen Effect of miR-26b-5p on progression of acute myeloid leukemia by regulating USP48-mediated Wnt/β-catenin pathway Yu Xie, Lin Tan, Kun Wu, Deyun Li, Chengping Li
Portal Digital Begell Biblioteca digital da Begell eBooks Diários Referências e Anais Coleções de pesquisa Políticas de preços e assinaturas Begell House Contato Language English 中文 Русский Português German French Spain