Inscrição na biblioteca: Guest
Portal Digital Begell Biblioteca digital da Begell eBooks Diários Referências e Anais Coleções de pesquisa
Critical Reviews™ in Eukaryotic Gene Expression
Fator do impacto: 2.156 FI de cinco anos: 2.255 SJR: 0.649 SNIP: 0.599 CiteScore™: 3

ISSN Imprimir: 1045-4403
ISSN On-line: 2162-6502

Volume 30, 2020 Volume 29, 2019 Volume 28, 2018 Volume 27, 2017 Volume 26, 2016 Volume 25, 2015 Volume 24, 2014 Volume 23, 2013 Volume 22, 2012 Volume 21, 2011 Volume 20, 2010 Volume 19, 2009 Volume 18, 2008 Volume 17, 2007 Volume 16, 2006 Volume 15, 2005 Volume 14, 2004 Volume 13, 2003 Volume 12, 2002 Volume 11, 2001 Volume 10, 2000 Volume 9, 1999 Volume 8, 1998 Volume 7, 1997 Volume 6, 1996 Volume 5, 1995 Volume 4, 1994

Critical Reviews™ in Eukaryotic Gene Expression

DOI: 10.1615/CritRevEukaryotGeneExpr.2014007569
pages 29-38

The Different Molecular Mechanisms of Mitophagy Between Yeast and Mammals

Ying Song
Department of Pharmacology, Zhejiang University of Technology, 18# Chaowang Road, Hangzhou City, Zhejiang Province 310014, P.R. China
Yan Xiao
Department of Pharmacology, Zhejiang University of Technology, Hangzhou Chaowang Road 18#, Zhejiang, 310014, P.R. China
Jia-Ming Wang
Department of Life Sciences Beking University , Yiheyuan Road 5#, Haidian District, Beijing, 100871, P.R. China
Qi Chen
Third hospital of Hangzhou, West Lake Road 38#, 310016, P.R. China


The mitochondrion is the site of energy metabolism inside the cell; which produces ATP for vital activities. The accumulation of damaged mitochondria affects cell survival, these organelles are removed via mitophagy to maintain cell vitality. Currently, mitophagy is a hot topic in life science research. Understanding the role of mitophagy in pathogenesis and its association with the genesis of disease is important for developing treatments for many human diseases. Here, we summarize current progress in the study of mitophagy and describe the different molecular mechanisms of mitophagy between yeast and mammals, as well as related diseases.

Articles with similar content:

BMP Signaling Pathways in Cartilage and Bone Formation
Critical Reviews™ in Eukaryotic Gene Expression, Vol.11, 2001, issue 1-3
Andrea Hoffmann, Gerhard Gross
Osteoclastogenesis: The Role of Calcium and Calmodulin
Critical Reviews™ in Eukaryotic Gene Expression, Vol.15, 2005, issue 1
Xu Feng, Liang Zhang, Jay M. McDonald, Nasser Said-Al-Naief
Nitric Oxide in Cerebral Ischemic Neurodegeneration and Excitotoxicity
Critical Reviews™ in Neurobiology, Vol.12, 1998, issue 3
Paul J. L. M. Strijbos
Twenty Years on: What Do We Really Know about Ewing Sarcoma and What Is the Path Forward?
Critical Reviews™ in Oncogenesis, Vol.20, 2015, issue 3-4
Elizabeth Lawlor, Poul H. Sorensen
Activation of Mammalian Toll-like Receptors by Endogenous Agonists
Critical Reviews™ in Immunology, Vol.23, 2003, issue 1-2
Gregory J. Brunn, Jeffrey L. Platt, Geoffrey B. Johnson