Publicou 4 edições por ano
ISSN Imprimir: 2155-014X
ISSN On-line: 2155-0158
Single-Channel Ion Currents in the Nuclear Envelope of Rat Cardiomyocytes
RESUMO
Using the patch clamp technique in nucleus attached configuration, we have found that the nuclear membrane of rat cardiomyocytes contains different types of ion channels with conductances in the range from 10 to 400 pSm. In particular, we recorded inositol 1,4,5-trisphosphate receptors with conductance of (384 ± 5) pS, as well as cation channels with conductance of (209 ± 13) pS which are similar to large-conductance (LCC)-channels, previously reported in neurons. In addition, we have found at least two types of ion channels with significantly higher conductance than that of LCC-channels, and several types of ion channels with lower conductance (10 – 90 pSm).
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Tarnopolskaya O., Kotlyarova A., Ion currents registration through LCC-channels of the nuclear membrane: a chronobiological aspect, Bulletin of Taras Shevchenko National University of Kyiv. Series: Biology, 83, 4, 2020. Crossref