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International Journal of Medicinal Mushrooms

Publicou 12 edições por ano

ISSN Imprimir: 1521-9437

ISSN On-line: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Evaluation of Anticholinesterase and Inflammation Inhibitory Activity of Medicinal Mushroom Phellinus pini (Basidiomycetes) Fruiting Bodies

Volume 18, Edição 11, 2016, pp. 1011-1022
DOI: 10.1615/IntJMedMushrooms.v18.i11.60
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RESUMO

Phellinus pini, a medicinal mushroom, has been used as folk medicine in Asian countries for treating ailments such as cancer and gastrointestinal diseases. In this study we evaluated in vitro the antidementia and anti-inflammatory activities of Ph. Pini fruiting bodies. Eleven phenol compounds were detected by high-performance liquid chromatography analysis. Acetylcholinesterase and butyrylcholinesterase inhibitory effects of a methanol extract and a hot water extract were moderate and comparable with those of galanthamine, the standard drug used to treat the early stages of Alzheimer's disease. The methanol extract had a neuroprotective effect against glutamate-induced cytotoxicity on PC-12 cells at concentration ranging from 20 to 40 µg/mL. The mushroom extracts also inhibited the production of nitric oxide and the expression of inducible nitric oxide synthase in lipopolysaccharide-induced RAW 264.7 macrophages, and they significantly inhibited in vivo carrageenan-induced hind-paw edema in rats. Therefore, it is suggested that Ph. Pini fruiting bodies possess anticholinesterase and anti-inflammatory effects.

CITADO POR
  1. Nowacka-Jechalke Natalia, Olech Marta, Nowak Renata, Mushroom Polyphenols as Chemopreventive Agents, in Polyphenols: Prevention and Treatment of Human Disease, 2018. Crossref

  2. Sun Yuqing, Zhong Shi, Yu Jiaqi, Zhu Jianxun, Ji Dongfeng, Hu Guiyan, Wu Chongming, Li Yougui, Singh Udai P., The aqueous extract of Phellinus igniarius (SH) ameliorates dextran sodium sulfate-induced colitis in C57BL/6 mice, PLOS ONE, 13, 10, 2018. Crossref

  3. Deveci Ebru, Tel-Çayan Gülsen, Duru Mehmet Emin, Öztürk Mehmet, Chemical constituents of Porodaedalea pini mushroom with cytotoxic, antioxidant and anticholinesterase activities, Journal of Food Measurement and Characterization, 13, 4, 2019. Crossref

  4. Li Xia, Gao Jie, Li Miaomiao, Cui Hao, Jiang Wei, Tu Zong-cai, Yuan Tao, Aromatic Cadinane Sesquiterpenoids from the Fruiting Bodies of Phellinus pini Block SARS-CoV-2 Spike–ACE2 Interaction, Journal of Natural Products, 84, 8, 2021. Crossref

  5. Badalyan Susanna M., Rapior Sylvie, The Neurotrophic and Neuroprotective Potential of Macrofungi, in Medicinal Herbs and Fungi, 2021. Crossref

  6. Rai Sachchida Nand, Mishra Divya, Singh Payal, Vamanu Emanuel, Singh M.P., Therapeutic applications of mushrooms and their biomolecules along with a glimpse of in silico approach in neurodegenerative diseases, Biomedicine & Pharmacotherapy, 137, 2021. Crossref

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