Inscrição na biblioteca: Guest
Portal Digital Begell Biblioteca digital da Begell eBooks Diários Referências e Anais Coleções de pesquisa
International Journal of Medicinal Mushrooms
Fator do impacto: 1.423 FI de cinco anos: 1.525 SJR: 0.431 SNIP: 0.716 CiteScore™: 2.6

ISSN Imprimir: 1521-9437
ISSN On-line: 1940-4344

Volumes:
Volume 22, 2020 Volume 21, 2019 Volume 20, 2018 Volume 19, 2017 Volume 18, 2016 Volume 17, 2015 Volume 16, 2014 Volume 15, 2013 Volume 14, 2012 Volume 13, 2011 Volume 12, 2010 Volume 11, 2009 Volume 10, 2008 Volume 9, 2007 Volume 8, 2006 Volume 7, 2005 Volume 6, 2004 Volume 5, 2003 Volume 4, 2002 Volume 3, 2001 Volume 2, 2000 Volume 1, 1999

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushrooms.v7.i3.400
392 pages

Comparative Analysis of Cordycepin, Minerals, and Vitamins on Cultivation Media of Cordyceps militaris (L.:Fr.) Link

Soo-Muk Cho
Agriproduct Processing Division, Rural Resources Development Institute, NIAST, RDA, Suwon 441-853, S. Korea
Sung-Hyeon Lee
Agriproduct Processing Division, Rural Resources Development Institute, NIAST, RDA, Suwon 441-853, S. Korea
Young-Min Lee
Agriproduct Processing Division, Rural Resources Development Institute, NIAST, RDA, Suwon 441-853, S. Korea
Jong-Deok Hong
Korea National Agricultural College Business Incubating Center, RDA, Hwasung, Kyungki-Do 11-1, S. Korea
Hye-Kyung Chun
Agriproduct Processing Division, Rural Resources Development Institute, NIAST, RDA, Suwon 441-853, S. Korea
Hong-Ju Park
Korea National Agricultural College Business Incubating Center, RDA, Hwasung, Kyungki-Do 11-1, S. Korea

RESUMO

Cordyceps militaris, belonging to Clavicipitaceae, Ascomycotina, has long been considered to have natural medicinal properties, compounds that are homeostatic, mycolytic, and antiasthmatic, and it is used as an expectorant. It has also been found as an insect parasite under humid ground in the mountains of Korea, China, and Japan.
Cordycepin, a nucleoside analogue 3′-deoxy-adenosine with a broad spectrum of biological activity, was first extracted from C. Militaris. The quantitative analysis of cordycepin is important in studies of their functions in biological systems.
The purpose of the present study was to develop a simple, fast, and sensitive LC/MS method for simultaneous separation and determination of an active component in the oriental medicinal mushroom mentioned above. Based on this work, the contents of cordycepin in C. militaris fruiting, cultivated on various media, were determined and compared. And also, the nutritional components such as minerals and vitamins were determined in order to provide useful information to the consumers. The optimum separation for cordycepin was achieved using a solvent gradient consisting of a mixture of 0.1% formic acid in methanol (solvent B) in a background of 0.1% formic acid in water (solvent A) as a mobile phase and a 3.0×150 mm Waters Xtera column. Selective ion monitoring (SIR) mode ([M+H] + at m/z 252) was used for quantitative analysis of cordycepin. The cultivated C. militaris on various media contained 1∼14 mg/g of cordycepin, 0.65∼1.08 mg% of thiamine, 0.86∼7.17 mg% of riboflavin, and 3.01∼5.26 mg% of niacin. The content of mineral components varied on categories, especially on those containing 500∼3500 mg% of potassium as a major mineral. Cordycepin, niacin, and potassium were much higher in the fruiting cultivated with soy powder media (gold 10) than other media.


Articles with similar content:

Study of Melanin Complex from Medicinal Mushroom Phellinus robustus (P. Karst.) Bourd. et Galz. (Aphyllophoromycetideae)
International Journal of Medicinal Mushrooms, Vol.9, 2007, issue 2
Nina A. Bisko, Victor V. Shcherba, Nadezda Yu. Mitropolskaya
Content of Lipids, Fatty Acids, and Fucoxanthin in Branches of Different Ages of Cystoseira barbata (Stackhouse) C. Agardh (Phaeophyceae)
International Journal on Algae, Vol.21, 2019, issue 4
A. V. Prazukin, E. V. Gureeva , M. V. Nechoroshev, V. I. Ryabushko , A. N. Kamnev
Chemical Composition and Nutritional and Medicinal Value of Fruit Bodies and Submerged Cultured Mycelia of Culinary-Medicinal Higher Basidiomycetes Mushrooms
International Journal of Medicinal Mushrooms, Vol.16, 2014, issue 3
Nachshol Cohen, Jacob Cohen, Yu-Hsuan Li, Solomon P. Wasser, Jeng-Leun Mau, Yi-Chi Yang, Hui-Tzu Yu, Mikheil D. Asatiani, Vinay K. Varshney
Optimization of Cultivation Conditions of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes) for the Highest Antioxidant Activity and Antioxidant Content
International Journal of Medicinal Mushrooms, Vol.21, 2019, issue 4
Jun-Fang Lin, Xin-yue Guo, Hai-wei Lou, Xin-chao Zhang, Liqiong Guo
Purification and Characterization of a Novel Protease from the Inky Cap Mushroom, Coprinopsis atramentaria (Agaricomycetes)
International Journal of Medicinal Mushrooms, Vol.20, 2018, issue 4
Hexiang Wang, Wenwen Chen, Xueran Geng, Tzi Bun Ng, Weiwei Zhang