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International Journal of Medicinal Mushrooms

Publicou 12 edições por ano

ISSN Imprimir: 1521-9437

ISSN On-line: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Antioxidant Activity of Extracts from the Red-Belt Conk Medicinal Mushroom, Fomitopsis pinicola (Agaricomycetes), and Its Modulatory Effects on Antioxidant Enzymes

Volume 18, Edição 6, 2016, pp. 501-508
DOI: 10.1615/IntJMedMushrooms.v18.i6.40
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RESUMO

The antioxidant capacity of Fomitopsis pinicola extracts was determined based on DPPH radical scavenging activites. Their total phenolic and flavonoid contents were also investigated. Antioxidant enzymes are important in controlling oxidative stress and maintaining cellular homeostatis. They can protect cells from the deleterious effects of reactive oxygen species and prevent the development of degenerative diseases such as Alzhemier disease, Parkinson disease, cancer, and even aging. In this regard, the modulatory activities of F. pinicola extracts on the antioxdant enzymes superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) were also investigated. The half-maximal inhibitory concentration for DPPH radical scavenging capacity of the pure and 70% ethanol extracts were determined as 0.178 ± 0.004 and 0.300 ± 0.005 mg/mL, respectively. Total phenolic contents of the pure and 70% ethanol extracts were determined as 313.2 ± 5.8 and 278.0 ± 2.9 mg gallic acid equivalents/g extract, respectively. The total flavonoid contents of the pure and 70% ethanol extracts of F. pinicola were determined as 93.8 ± 1.6 and 100.4 ± 4.5 mg quercetin equivalents/g extract, respectively. Both the pure and 70% ethanol extracts (1-10 mg/ml) were investigated for their activities on GPx, SOD, and CAT enzymes in vitro; maximum concentrations of both F. pinicola extracts effectively activated the GPx and SOD enzymes at around 20-35% and the CAT enzyme at 2-12%. Gallic acid is one the main ingredients of F. pinicola extract; therefore, the gallic acid content of the extract was determined by high-performance liquid chromatography, and its corresponding modulatory activities on the same enzymes were also investigated in vitro. The results indicate that the beneficial effects of F. pinicola might be related to its high antioxidant potential, its high gallic acid content, and its ability to modify and activate antioxidant enzymes.

CITADO POR
  1. Dizeci Naz, Onar Okan, Karaca Basar, Demirtas Nergiz, Coleri Cihan Arzu, Yildirim Ozlem, Comparison of the chemical composition and biological effects of Clitocybe nebularis and Infundibulicybe geotropa, Mycologia, 2021. Crossref

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