Inscrição na biblioteca: Guest
Portal Digital Begell Biblioteca digital da Begell eBooks Diários Referências e Anais Coleções de pesquisa
International Journal of Medicinal Mushrooms
Fator do impacto: 1.423 FI de cinco anos: 1.525 SJR: 0.431 SNIP: 0.716 CiteScore™: 2.6

ISSN Imprimir: 1521-9437
ISSN On-line: 1940-4344

Volume 22, 2020 Volume 21, 2019 Volume 20, 2018 Volume 19, 2017 Volume 18, 2016 Volume 17, 2015 Volume 16, 2014 Volume 15, 2013 Volume 14, 2012 Volume 13, 2011 Volume 12, 2010 Volume 11, 2009 Volume 10, 2008 Volume 9, 2007 Volume 8, 2006 Volume 7, 2005 Volume 6, 2004 Volume 5, 2003 Volume 4, 2002 Volume 3, 2001 Volume 2, 2000 Volume 1, 1999

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushr.v12.i3.80
pages 287-297

Comparison of Some Metabolites Among Cultured Mycelia of Medicinal Fungus, Ophiocordyceps sinensis (Ascomycetes) from Different Geographical Regions

Caihong Dong
State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China
Yi-Jian Yao
State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China; ITPB-IMCAS Key Joint Laboratory of Alpine Fungi, Lhasa, China


Ophiocordyceps sinensis, also named Dong Chong Xia Cao, is one of the best-known Chinese medical fungus, with great benefits to human health and huge economical values. In the present study, cultured mycelia were obtained from submerged cultures with 18 authentic and representative strains from different origins on the Tibetan plateau. The contents of the main metabolites, including adenosine, uridine, guanosine, cordycepin, and D-mannitol, were then determined. There was no obvious trend in the amount of nucleosides between the cultured O. sinensis mycelia and natural products. Among the tested nucleosides, uridine showed the highest concentration. Cordycepin has been confirmed in submerged cultured mycelia. Natural products have a significantly higher content of D-mannitol compared with the submerged cultured mycelia. Based on the content of nucleosides and D-mannitol, hierarchical clustering analysis was performed. The tested samples were divided into two main clusters for cultured mycelia and natural products, respectively. The cultured mycelia of strains from different regions did not group together, suggesting that sample diversity had a greater effect on metabolite content than did the geographical origin. The results also suggested that strain selection is important when O. sinensis is used to manufacture health foods.

Articles with similar content:

Preparation of Novel Culinary-Medicinal Mushroom Products Using Solid-State Fermentation and Their Taste Quality
International Journal of Medicinal Mushrooms, Vol.11, 2009, issue 2
Yu-Ling Lee, Tsai-Ping Wu, Hui-Ching Kuo, Shao-Yu Jian, Wan-Lih Huang, Chih-Hung Liang
Cloning of Mating-Type Gene MAT1-1 from the Caterpillar Medicinal Mushroom, Cordyceps militaris (Ascomycetes) Using TAIL-PCR Technology
International Journal of Medicinal Mushrooms, Vol.16, 2014, issue 5
Xuan-Wei Zhou, Dan-Dan Shi, Zhen-Hua Gong, Wei-Ran Cong, Hui Guo
Identification of a New Fungal Pathogen Causing White Villous Disease on the Fruiting Body of the Culinary-Medicinal Mushroom Auricularia auricula-judae (Agaricomycetes) in China
International Journal of Medicinal Mushrooms, Vol.19, 2017, issue 2
Li-Ping Yu, Jie-Chi Zhang, Xiao-Dong Dai, Jia-Ning Liu, Qing-Fang Ma, Zeng-Hua Han, Yin-Peng Ma, Xiao-Yong Wang, Xiang-Hui Kong, Pi-Qi Zhang
Identification of Chinese Caterpillar Medicinal Mushroom, Ophiocordyceps sinensis (Ascomycetes) from Counterfeit Species
International Journal of Medicinal Mushrooms, Vol.19, 2017, issue 12
Xiaolong Zhang, Xian-Long Cheng, Shuangcheng Ma, Wenjuan Zhang, Ping Zhang, Minghua Li, Yan Shi, Feng Wei
Increasing of the Contain of Carotenoids in Caterpillar Mushroom, Cordyceps militaris (Ascomycetes) by Using the Fungal Elicitors Cultivation
International Journal of Medicinal Mushrooms, Vol.21, 2019, issue 12
Zhiwei Ye, Jun-Fang Lin, Fan Yun, Linzhi Kang, Hongbiao Tang, Cong Liu, Liqiong Guo, Hua Wang