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International Journal of Medicinal Mushrooms

Publicou 12 edições por ano

ISSN Imprimir: 1521-9437

ISSN On-line: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Antitumor Activity and Hematopoietic Response of a b-Glucan Extracted from an Edible and Medicinal Mushroom Sparassis crispa Wulf.: Fr. (Aphyllophoromycetideae)

Volume 4, Edição 1, 2002, 14 pages
DOI: 10.1615/IntJMedMushr.v4.i1.20
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RESUMO

Sparassis crispa Wulf.: Fr. is an edible and medicinal mushroom recently cultivated in Japan. It contains a high content (~ 40%) of 6-branched 1,3-b-D-glucan showing antitumor activity. Oral administration of the (b-glucan fraction CA1, extracted with cold sodium hydroxide, enhanced the hematopoietic response in cyclophosphamide (CY)-induced leukopenic mice assessed by white blood cell count. Analyzing the leukocyte population by flow cytometry, the rate of leukocyte recovery in CY-administered mice was different in each population, such as granulocyte, monocyte, natural killer cell, В cell, Т cell, and so on. Administration of CA1 modulated the recovery rate of each population. In Peyer's patches, recovery of the T/B ratio was faster than in the control group. In in vitro, CY-treated spleen cell culture, interleukin-6 and interferon-g production was enhanced by CA1 treatment. These facts strongly suggested that the enhanced hematopoietic response by CA1 is due to enhanced cytokine production.

CITADO POR
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