Publicou 12 edições por ano
ISSN Imprimir: 1521-9437
ISSN On-line: 1940-4344
IF:
1.2
5-Year IF:
1.4
Immediacy Index:
0.3
Eigenfactor:
0.00066
JCI:
0.34
SJR:
0.274
SNIP:
0.41
CiteScore™::
2.8
H-Index:
37
Indexed in
Immunomodulatory Effects of the Stout Camphor Medicinal Mushroom, Taiwanofungus camphoratus (Agaricomycetes)-Based Health Food Product in Mice
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RESUMO
Taiwanofungus camphoratus is a unique medicinal mushroom endemic to Taiwan, and it is used as a folk medicine in East Asian countries. The aim of the present study was to investigate the immunomodulatory effects of "leader Antrodia cinnamomea capsule" (LAC), a health food product containing solid-state cultivated mycelial powder of T. camphoratus. For the in vivo studies, mice were orally administered LAC (76, 250, and 760 mg/kg b.w.) for 30 days, and its effects on cell-mediated humoral immune function were examined. The results of the concanavalin A-induced splenic lymphocyte proliferation test showed that LAC significantly increased splenic lymphocyte proliferation compared with the control. In addition, serum hemolysin analysis showed that LAC treatment significantly increased the half value of serum hemolysin (HC50) in mice compared with the control. Moreover, treatment with LAC significantly increased the phagocytic index as measured by carbon clearance and natural killer cell activity. Taken together, these findings provide strong evidence that LAC can modulate immune function.
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Lin Liang-Hung, Chi Ching-Hsin, Zhang Xiao-Han, Chen Ying-Ju, Wang Ming-Fu, Immunomodulatory Effects of Fruiting Body Extract and Solid-State-Cultivated Mycelia of Taiwanofungus camphoratus, Nutrients, 11, 9, 2019. Crossref
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Lin Jian-Yu, Chen Mei-Chun, Chiu Emerson, Genotoxicity and subchronic toxicity studies of <i>Taiwanofungus camphoratus</i> extract, Fundamental Toxicological Sciences, 6, 3, 2019. Crossref
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Hung Hsin-Yi, Hung Chin-Chuan, Liang Jun-Weil, Chen Chin-Fu, Chen Hung-Yi, Shieh Po-Chuen, Kuo Ping-Chung, Wu Tian-Shung, Constituents and Anti-Multidrug Resistance Activity of Taiwanofungus camphoratus on Human Cervical Cancer Cells, Molecules, 24, 20, 2019. Crossref
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de Oliveira Jonatas Rafael, Camargo Samira Esteves Afonso, de Oliveira Luciane Dias, Rosmarinus officinalis L. (rosemary) as therapeutic and prophylactic agent, Journal of Biomedical Science, 26, 1, 2019. Crossref
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Wang Caicheng, Zhang Weiwei, Wong Jack Ho, Ng Tzibun, Ye Xiujuan, Diversity of potentially exploitable pharmacological activities of the highly prized edible medicinal fungus Antrodia camphorata, Applied Microbiology and Biotechnology, 103, 19, 2019. Crossref
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Wang Ya-Yun, Hsieh Yu-Hsin, Kumar K. J. Senthil, Hsieh Han-Wen, Lin Chin-Chung, Wang Sheng-Yang, The Regulatory Effects of a Formulation of Cinnamomum osmophloeum Kaneh and Taiwanofungus camphoratus on Metabolic Syndrome and the Gut Microbiome, Plants, 9, 3, 2020. Crossref
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Liao Yu-Tso, Huang Kai-Wen, Chen Wan-Jing, Lai Tzung-Hsien, A Botanical Drug Extracted From Antrodia cinnamomea: A First-in-human Phase I Study in Healthy Volunteers, Journal of the American Nutrition Association, 2022. Crossref