Publicou 12 edições por ano
ISSN Imprimir: 1521-9437
ISSN On-line: 1940-4344
IF:
1.2
5-Year IF:
1.4
Immediacy Index:
0.3
Eigenfactor:
0.00066
JCI:
0.34
SJR:
0.274
SNIP:
0.41
CiteScore™::
2.8
H-Index:
37
Indexed in
Cultivation of Medicinal Caterpillar Fungus, Cordyceps militaris (Ascomycetes), and Production of Cordycepin Using the Spent Medium from Levan Fermentation
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RESUMO
A process of tandem cultivation for the production of green and invaluable bioproducts (levan and Cordycepes militaris) useful for medical applications has been successfully developed. The process involves first cultivating Bacillus subtilis strain natto in sucrose medium to produce levan, followed by the subsequent cultivation of C. militaris in liquid- and solid-state cultures using the spent medium from levan fermentation as substrates. The factors affecting the cell growth and production of metabolites of C. militaris were investigated, and the various metabolites produced in the culture filtrate, mycelia, and fruiting body were analyzed. In addition, cordycepin was prepared from the solid waste medium of C. militaris. This is an excellent example in the development of cost effective biorefineries that maximize useful product formation from the available biomass. The preparation of cordycepin from solid waste medium of C. militaris using a method with high extraction efficiency and minimum solvent usage is also environmentally friendly.
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Jiang Keqing, Han Richou, Rhf1 gene is involved in the fruiting body production of Cordyceps militaris fungus, Journal of Industrial Microbiology and Biotechnology, 42, 8, 2015. Crossref
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Wang Hsiu-Ju, Pan Meng-Chun, Chang Chao-Kai, Chang Shu-Wei, Hsieh Chang-Wei, Optimization of Ultrasonic-Assisted Extraction of Cordycepin from Cordyceps militaris Using Orthogonal Experimental Design, Molecules, 19, 12, 2014. Crossref
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Lin Qunying, Long Liangkun, Wu Liangliang, Zhang Fenglun, Wu Shuling, Zhang Weiming, Sun Xiaoming, Evaluation of different agricultural wastes for the production of fruiting bodies and bioactive compounds by medicinal mushroomCordyceps militaris, Journal of the Science of Food and Agriculture, 97, 10, 2017. Crossref
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Phan Chia-Wei, Wang Joon-Keong, Cheah Shiau-Chuen, Naidu Murali, David Pamela, Sabaratnam Vikineswary, A review on the nucleic acid constituents in mushrooms: nucleobases, nucleosides and nucleotides, Critical Reviews in Biotechnology, 38, 5, 2018. Crossref
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Zhang Wencheng, Li Bing, Dong Xiuli, Wang Bingsong, Wu Ze-Yu, Enzyme-assisted extraction of cordycepin and adenosine from cultured Cordyceps militaris and purification by macroporous resin column chromatography, Separation Science and Technology, 52, 8, 2017. Crossref
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Shi Hao, Zhang Min, Bhandari Bhesh, Wang Yuchuan, Yi Sifu, Effects of superfine grinding on the properties and qualities of Cordyceps militaris and its spent substrate , Journal of Food Processing and Preservation, 43, 11, 2019. Crossref
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Cheong Peter Chiew Hing, Tan Chon Seng, Fung Shin Yee, Medicinal Mushrooms: Cultivation and Pharmaceutical Impact, in Biology of Macrofungi, 2018. Crossref
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Turło Jadwiga, The biotechnology of higher fungi - current state and perspectives, Folia Biologica et Oecologica, 10, 2014. Crossref
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Thy Trần Thanh, Nghiên cứu môi trường rắn làm tăng hàm lượng cordycepin và adenosine của nấm Cordyceps militaris, Can Tho University Journal of Science, 55(Công nghệ Sin, 2019. Crossref
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Johri Srishti, Nair Yash Vignesh, Selvapandiyan A., Cultivation and Medicinal Uses of Cordyceps militaris (L.) Link: A Revolutionary Entomopathogenic Fungus, in Biology, Cultivation and Applications of Mushrooms, 2022. Crossref
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Liu Ziying, Leng Guihua, Wen Jingbai, Deng Ganqi, Jiang Jiayao, Cordycepin production by a novel endophytic fungus Irpex lacteus CHG05 isolated from Cordyceps hawkesii Gray, Folia Microbiologica, 2022. Crossref
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Chiu Ching-Peng, Hwang Tsong-Long, Chan You, El-Shazly Mohamed, Wu Tung-Ying, Lo I-Wen, Hsu Yu-Ming, Lai Kuei-Hung, Hou Ming-Feng, Yuan Shyng-Shiou, Chang Fang-Rong, Wu Yang-Chang, Research and development of Cordyceps in Taiwan, Food Science and Human Wellness, 5, 4, 2016. Crossref