Inscrição na biblioteca: Guest
Portal Digital Begell Biblioteca digital da Begell eBooks Diários Referências e Anais Coleções de pesquisa
International Journal of Medicinal Mushrooms
Fator do impacto: 1.423 FI de cinco anos: 1.525 SJR: 0.433 SNIP: 0.661 CiteScore™: 1.38

ISSN Imprimir: 1521-9437
ISSN On-line: 1940-4344

Volumes:
Volume 21, 2019 Volume 20, 2018 Volume 19, 2017 Volume 18, 2016 Volume 17, 2015 Volume 16, 2014 Volume 15, 2013 Volume 14, 2012 Volume 13, 2011 Volume 12, 2010 Volume 11, 2009 Volume 10, 2008 Volume 9, 2007 Volume 8, 2006 Volume 7, 2005 Volume 6, 2004 Volume 5, 2003 Volume 4, 2002 Volume 3, 2001 Volume 2, 2000 Volume 1, 1999

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushr.v11.i4.60
pages 395-408

Antioxidant and Antigenotoxicity Activities of Extracts from Liquid Submerged Culture of Culinary-Medicinal Ferula Oyster Mushroom, Pleurotus eryngii (DC.) Quél. var. ferulae (Lanzi) Sacc. (Agaricomycetideae)

Shu-Hui Hu
Department of Nutrition and Dietetics, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan; Department of Medical Laboratory Science and Biotechnology, Kaohsiung Medical University, Kaohsiung, Taiwan
Juang-Lin Lien
Department of Seafood Science, National Kaohsiung Marine University, No. 142, Haijhuan Rd., Kaohsiung, Taiwan, 807
Shu-Ling Hsieh
Department of Nutrition and Health Science, Fooyin University, Ta-liao Shiang, Kaohsiung, Taiwan, 831
Jinn-Chyi Wang
Department of Food Science and Technology, Tajen University, Shin-Erh Village, Yen-Pu Shiang, Pingtung, Taiwan
Sue-Joan Chang
Department of Life Science, National Cheng Kung University, Tainan, Taiwan, 701

RESUMO

The ferula oyster mushroom (Pleurotus eryngii var. ferulae) is medicinal, edible, and delicious. Response surface methodology was used to determine the optimal conditions for the production of P. eryngii var. ferulae biomass in liquid submerged culture. Lyophilized mycelium was subjected to two water extracts and two elutes through column chromatography using methanol-ethyl acetate-dichloromethane (referred to as EAM and CHE, respectively). In addition, the crude protein and water-soluble polysaccharides were extracted from the cultured broth. Six samples were tested to explore their antigenotoxicity with the Ames test and a rec-assay, as well as antioxidant activities in in vivo and in vitro tests. EAM had the highest 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical-scavenging activity and ferric-reducing ability. Moreover, hamster serum showed the highest activities of glutathione peroxidase and superoxide dismutase after EAM was administered at a dose of 0.3 g kg−1 body weight daily among all tested samples. Meanwhile, the EAM group displayed significantly higher activities of the two enzymes than did the control group. In the antimutagenicity test, EAM exhibited the highest inhibition rate against every tested mutagen at a low concentration of 0.08 mg mL−1 and a high concentration of 0.3 mg mL−1 in each plate, and it also had the highest anti-DNA-damaging activity among all test samples. EAM displayed the highest antigenotoxicity effect, followed by CHE, when using water-insoluble extracts, and CP was the highest one, followed by water extract (100°C, 30 minutes), water extract (60°C, 30 minutes), and SPPF, when using water-soluble extracts. The major constituents of EAM and CHE were identified as ergosterol and 2-pentanol, respectively. Some extracts from P. eryngii var. ferulae have significant antioxidant activity and are strong antigenotoxic agents.


Articles with similar content:

In Vitro Antioxidant and In Vivo Hypolipidemic Effects of the King Oyster Culinary-Medicinal Mushroom, Pleurotus eryngii var. ferulae DDL01 (Agaricomycetes), in Rats with High-Fat Diet–Induced Fatty Liver and Hyperlipidemia
International Journal of Medicinal Mushrooms, Vol.19, 2017, issue 2
Dae-Won Kim, Sung-Jun Kim, Jun-Hui Choi, Seung Kim
Genoprotective Capacity of Alternatively Cultivated Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Basidiocarps
International Journal of Medicinal Mushrooms, Vol.18, 2016, issue 12
Vladan Bajic, Jelena Vukojević, Lada Živković, Mirjana Stajic, Jasmina Ćilerdžić, Biljana Spremo-Potparević
Antiprotozoal Activity and Mitogenic Effect of Mycelium of Culinary-Medicinal Shiitake Mushroom Lentinus edodes (Berk.) Singer (Agaricomycetideae)
International Journal of Medicinal Mushrooms, Vol.6, 2004, issue 2
Susanna M. Badalyan
Antifungal, Antioxidative, and Genoprotective Properties of Extracts from the Blushing Bracket Mushroom, Daedaleopsis confragosa (Agaricomycetes)
International Journal of Medicinal Mushrooms, Vol.19, 2017, issue 6
Ivan Milovanović, Jelena Vukojević, Lada Živković, Aleksandar Knežević, Mirjana Stajić, Biljana Spremo-Potparević
Comparison of the Composition and Antioxidant Activities of Phenolics from the Fruiting Bodies of Cultivated Asian Culinary-Medicinal Mushrooms
International Journal of Medicinal Mushrooms, Vol.18, 2016, issue 10
Peter Chi Keung Cheung, Shaoling Lin, Lai Tsz Ching, Xinxin Ke