Inscrição na biblioteca: Guest
Portal Digital Begell Biblioteca digital da Begell eBooks Diários Referências e Anais Coleções de pesquisa
International Journal of Medicinal Mushrooms
Fator do impacto: 1.423 FI de cinco anos: 1.525 SJR: 0.431 SNIP: 0.661 CiteScore™: 1.38

ISSN Imprimir: 1521-9437
ISSN On-line: 1940-4344

Volumes:
Volume 21, 2019 Volume 20, 2018 Volume 19, 2017 Volume 18, 2016 Volume 17, 2015 Volume 16, 2014 Volume 15, 2013 Volume 14, 2012 Volume 13, 2011 Volume 12, 2010 Volume 11, 2009 Volume 10, 2008 Volume 9, 2007 Volume 8, 2006 Volume 7, 2005 Volume 6, 2004 Volume 5, 2003 Volume 4, 2002 Volume 3, 2001 Volume 2, 2000 Volume 1, 1999

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushrooms.v18.i10.50
pages 895-903

Free-Radical Scavenging Activities of Cultured Mycelia of Paecilomyces hepiali (Ascomycetes) Extracts and Structural Characterization of Bioactive Components by Nuclear Magnetic Resonance Spectroscopy

Lucia Ungvarska Mal'ucka
Department of Chemistry, Biochemistry and Biophysics, Institute of Pharmaceutical Chemistry, University of Veterinary Medicine and Pharmacy in Kosice, Kosice, Slovak Republic
Jarmila Harvanova
Department of Chemistry, Biochemistry, and Biophysics, Institute of Pharmaceutical Chemistry, University of Veterinary Medicine and Pharmacy, Kosice, Slovak Republic
Martin Pavlik
Faculty of Forestry, Department of Integrated Forest and Landscape Protection, Technical University in Zvolen, Zvolen, Slovak Republic
Martin Rajtar
Mykoforest – Martin Rajtar, Velčice, Slovak Republic
Lukas Jarosciak
Department of Chemistry, Biochemistry and Biophysics, Institute of Pharmaceutical Chemistry, University of Veterinary Medicine and Pharmacy in Kosice, Kosice, Slovak Republic

RESUMO

Current research is focused on testing the cultivation of Paecilomyces hepiali mycelia on various plant substrates and producing fungus or mycelial biomass with qualitatively interesting substances. P. hepiali mycelia was cultivated using solid-state fermentation of different substrates. Mycelial biomass was then analyzed, and antioxidant activity was evaluated using the DPPH radical scavenging method for different ethanolic extracts based on a millet substrate (extract 1) or a chickpea substrate (extract 2). Extract 1 corresponds to a half-maximal DPPH radical inhibitory concentration of 1.73 mg/mL; the inhibitory concentration of ethanol extract 2 was almost 4.5 times higher at 7.92 mg/mL. Extracts 1 and 2 were separated into fractions by column chromatography and the chemical structures were determined for the substances that formed the most effective fraction of sample 1. The chemical structures of all compounds in the most active fraction of sample 1 were analyzed by 1H, 13C, distortionless enhancement by polarization transfer, correlation spectroscopy, heteronuclear single-quantum correlation spectroscopy, and heteronuclear multiple-bond correlation spectra.


Articles with similar content:

Polar Fractionation Affects the Antioxidant Properties of Methanolic Extracts from Species of Genus Phellinus Quel. (Higher Basidiomycetes)
International Journal of Medicinal Mushrooms, Vol.14, 2012, issue 6
Jesus Fernando Ayala-Zavala, Gustavo Adolfo Gonzalez-Aguilar, Martin Esqueda, Juan Manuel Leyva, Julio Jesumar Perez-Carlon, Manuel Reynaldo Cruz-Valenzuela, Edgar Moctezuma
Characterization and Antioxidant Activity of an Exopolysaccharide Produced by Rigidoporus microporus (Agaricomycetes)
International Journal of Medicinal Mushrooms, Vol.20, 2018, issue 4
Ran Panpan, Yan Wu, Xuewei Jia, Shuai Liu, Chunping Xu, Lili Qu
Bioactivity-Guided Isolation of Acetylcholinesterase Inhibitor from Ganoderma mediosinense (Agaricomycetes)
International Journal of Medicinal Mushrooms, Vol.21, 2019, issue 8
Arshdeep Kaur, Kudrat Randhawa, Varinder Singh, Richa Shri
Determination of the Antioxidant Activity and Polyphenol Contents of Wild Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (W.Curt. Fr.) P. Karst. (Higher Basidiomycetes) from Central Himalayan Hills of India
International Journal of Medicinal Mushrooms, Vol.13, 2011, issue 6
Prem Singh Negi, Zakwan Ahmed, Mohammed Mohsin
Antifungal, Antioxidative, and Genoprotective Properties of Extracts from the Blushing Bracket Mushroom, Daedaleopsis confragosa (Agaricomycetes)
International Journal of Medicinal Mushrooms, Vol.19, 2017, issue 6
Ivan Milovanović, Jelena Vukojević, Lada Živković, Aleksandar Knežević, Mirjana Stajić, Biljana Spremo-Potparević