Inscrição na biblioteca: Guest
Portal Digital Begell Biblioteca digital da Begell eBooks Diários Referências e Anais Coleções de pesquisa
International Journal of Medicinal Mushrooms
Fator do impacto: 1.423 FI de cinco anos: 1.525 SJR: 0.433 SNIP: 0.661 CiteScore™: 1.38

ISSN Imprimir: 1521-9437
ISSN On-line: 1940-4344

Volumes:
Volume 21, 2019 Volume 20, 2018 Volume 19, 2017 Volume 18, 2016 Volume 17, 2015 Volume 16, 2014 Volume 15, 2013 Volume 14, 2012 Volume 13, 2011 Volume 12, 2010 Volume 11, 2009 Volume 10, 2008 Volume 9, 2007 Volume 8, 2006 Volume 7, 2005 Volume 6, 2004 Volume 5, 2003 Volume 4, 2002 Volume 3, 2001 Volume 2, 2000 Volume 1, 1999

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushr.v10.i1.60
pages 49-53

In Vitro Anti-inflammatory Activity of Selected Japanese Higher Basidiomycetes Mushrooms

Esameldin E. Elgorashi
Department of Veterinary Pharmacology, Faculty of Agriculture, Tottori University, 4-101 Minami, Koyama, Tottori 680-8553, Japan
Nitaro Maekawa
The Tottori Mycological Institute, Kokoge 211, Tottori-shi, Tottori 689-1125, Japan
Hiroshi Satoh
Department of Veterinary Pharmacology, Faculty of Agriculture, Tottori University, 4-101 Minami, Koyama, Tottori 680-8553, Japan

RESUMO

Mycelial extracts (ethyl acetate and 70% ethanol) of 20 higher Basidiomycetes edible or medicinal mushrooms and culture media extracts (ethyl acetate and Butan-1-ol) were evaluated for in vitro anti-inflammatory activity using the cyclooxygenase-1 and -2 enzymes (COX-1 and -2). Generally, 70% ethanolic extracts showed lower inhibitory activity against both enzymes compared to ethyl acetate extracts. Of the mushrooms tested, the ethyl acetate extracts of Ganoderma applanata, Naematoloma sublateritium, Pleurotus eryngii, and P. salmoneostramineus showed the highest COX-2 inhibitory effects (IC50 values of 49.7, 80.6, 121.7, and 115.8 μg/mL, respectively) compared to COX-1 inhibition (IC50 values of 125.3, 156, 188.9, and 250 μg/mL, respectively). Of the culture media tested in this study, only the ethyl acetate extracts of the culture medium of Agrocybe cylindracea exhibited high inhibition of the COX-2 enzyme.


Articles with similar content:

Antimicrobial and Cytotoxic Activities of the Sulphur Shelf Medicinal Mushroom, Laetiporus sulphureus (Agaricomycetes), from Serbia
International Journal of Medicinal Mushrooms, Vol.18, 2016, issue 6
Tatjana P. Stanojkovic, Tatjana D. Kundakovic, Milan Kojic, Marina D. Kolundzic, Marina T. Milenkovic, Nada O. Grozdanic, Miroslav R. Dinic, Natasa E. Golic
Wild Edible Mushrooms from Turkey as Possible Anticancer Agents on HepG2 Cells Together with Their Antioxidant and Antimicrobial Properties
International Journal of Medicinal Mushrooms, Vol.18, 2016, issue 1
Bugrahan Emsen, Aytac Kocabas, Hicret Asli Yalcin, Gokhan Sadi, Deniz Irtem Kartal, Abdullah Kaya, Ahmet Altay
Antibacterial and Anti-Inflammatory Activities of Mycelia of a Medicinal Mushroom from Taiwan, Taiwanofungus salmoneus (Higher Basidiomycetes)
International Journal of Medicinal Mushrooms, Vol.15, 2013, issue 1
Shen-Shih Chiang, Jeng-Leun Mau, Shin-Yu Chen, Li-Ting Wang
Antioxidant Properties of Ethanolic Extracts from Culinary-Medicinal Button Mushroom Agaricus bisporus (J. Lange) Imbach (Agaricomycetideae) Harvested at Different Stages of Maturity
International Journal of Medicinal Mushrooms, Vol.10, 2008, issue 2
Jeng-Leun Mau, Tsai-Ping Wu, Shu-Yao Tsai, Shih-Jeng Huang
Assessment of Anti-inflammatory, Lipid Peroxidation and Acute Toxicity of Extracts Obtained From Wild Higher Basidiomycetes Mushrooms Collected From Akure (Southwest Nigeria)
International Journal of Medicinal Mushrooms, Vol.14, 2012, issue 6
Antonio Nieto-Camacho, Victor O. Oyetayo, Baldomero Esquivel Rodriguez, Manuel Jimenez