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International Journal of Medicinal Mushrooms
Fator do impacto: 1.423 FI de cinco anos: 1.525 SJR: 0.431 SNIP: 0.716 CiteScore™: 2.6

ISSN Imprimir: 1521-9437
ISSN On-line: 1940-4344

Volumes:
Volume 22, 2020 Volume 21, 2019 Volume 20, 2018 Volume 19, 2017 Volume 18, 2016 Volume 17, 2015 Volume 16, 2014 Volume 15, 2013 Volume 14, 2012 Volume 13, 2011 Volume 12, 2010 Volume 11, 2009 Volume 10, 2008 Volume 9, 2007 Volume 8, 2006 Volume 7, 2005 Volume 6, 2004 Volume 5, 2003 Volume 4, 2002 Volume 3, 2001 Volume 2, 2000 Volume 1, 1999

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushr.v13.i1.10
pages 1-6

Mechanism of Nitric Oxide Production in Macrophages Treated with Medicinal Mushroom Extracts (Review)

Mian Huang
College of Life Science, South China Normal University
Xiaodeng Mei
College of Life Science, South China Normal University
Song Zhang
College of Life Science, South China Normal University

RESUMO

Nitric oxide (NO) is a gas with highly reactive radicals and is an important signal molecule in living organisms with diverse pathophysiological functions. Inducible NO synthase (iNOS) can be expressed in macrophages and is able to induce NO production. Studies have proposed that mushroom extracts can promote or inhibit NO production in macrophages through acting on iNOS, nuclear factor kappa B, and other signaling pathways. This article is dedicated to the mechanism of mushroom extracts affecting NO secretion in macrophages.


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