RT Journal Article
ID 476ab02d44475732
A1 Li, Chuan Silvia
A1 Ayeni, Olufemi R.
A1 Sprague, Sheila
A1 Truong, Victoria
A1 Bhandari, Mohit
T1 Conservative Treatments, Surgical Treatments, and the KineSpring® Knee Implant System for Knee Osteoarthritis: A Systematic Review
JF Journal of Long-Term Effects of Medical Implants
JO JLT
YR 2013
FD 2013-12-13
VO 23
IS 2-03
SP 105
OP 149
K1 Knee
K1 osteoarthritis
K1 systematic review
K1 orthopaedics
K1 surgical treatment
K1 conservative treatment
AB Purpose: Knee osteoarthritis (OA) is a disease with a high global burden, and multiple treatment
options are available. In the current review we summarize the results of studies that have evaluated
treatments of knee OA, and we compare these results with an implantable load absorber called the
KineSpring® Knee Implant System.
Methods: We conducted a literature search of systematic reviews on treatment strategies for knee
OA. We pooled results for each treatment in three categories: pain, function, and stiffness. Then we
compared this data to that available for the KineSpring System.
Results: Medications and viscosupplementation show promising initial pain relief for knee OA.
Aerobic and resistance training, unicompartmental knee arthroplasty (UKA), and total knee arthroplasty
(TKA) showed a reduction in pain scores. High tibial osteotomy (HTO) generally improves
pain and function at 6 weeks, but long-term results are lacking. The KineSpring System demonstrated
significant improvements from baseline to 24 months, but direct comparative data are lacking.
Conclusions: Evidence for knee OA therapies suggests improved pain, stiffness, and functional outcomes.
Additional research is necessary to clearly delineate the advantages of various approaches
to guide practice.
PB Begell House
LK https://www.dl.begellhouse.com/journals/1bef42082d7a0fdf,3923dcfe34001ae4,476ab02d44475732.html