RT Journal Article ID 476ab02d44475732 A1 Li, Chuan Silvia A1 Ayeni, Olufemi R. A1 Sprague, Sheila A1 Truong, Victoria A1 Bhandari, Mohit T1 Conservative Treatments, Surgical Treatments, and the KineSpring® Knee Implant System for Knee Osteoarthritis: A Systematic Review JF Journal of Long-Term Effects of Medical Implants JO JLT YR 2013 FD 2013-12-13 VO 23 IS 2-03 SP 105 OP 149 K1 Knee K1 osteoarthritis K1 systematic review K1 orthopaedics K1 surgical treatment K1 conservative treatment AB Purpose: Knee osteoarthritis (OA) is a disease with a high global burden, and multiple treatment options are available. In the current review we summarize the results of studies that have evaluated treatments of knee OA, and we compare these results with an implantable load absorber called the KineSpring® Knee Implant System.
Methods: We conducted a literature search of systematic reviews on treatment strategies for knee OA. We pooled results for each treatment in three categories: pain, function, and stiffness. Then we compared this data to that available for the KineSpring System.
Results: Medications and viscosupplementation show promising initial pain relief for knee OA. Aerobic and resistance training, unicompartmental knee arthroplasty (UKA), and total knee arthroplasty (TKA) showed a reduction in pain scores. High tibial osteotomy (HTO) generally improves pain and function at 6 weeks, but long-term results are lacking. The KineSpring System demonstrated significant improvements from baseline to 24 months, but direct comparative data are lacking.
Conclusions: Evidence for knee OA therapies suggests improved pain, stiffness, and functional outcomes. Additional research is necessary to clearly delineate the advantages of various approaches to guide practice. PB Begell House LK https://www.dl.begellhouse.com/journals/1bef42082d7a0fdf,3923dcfe34001ae4,476ab02d44475732.html