RT Journal Article ID 4a9b5eee5c1483b9 A1 Mizuno, Takashi T1 Development of an Antitumor Biological Response Modifier from Phellinus linteus (Berk. et Curt.) Teng (Aphyllophoromycetideae) (Review) JF International Journal of Medicinal Mushrooms JO IJM YR 2000 FD 2000-03-01 VO 2 IS 1 OP 13 AB In Japan, three kinds of antitumor biological response modifiers-such as krestin (in 1977) from the mycelium of Trametes versicolor (= Coriolus versicolor), lentinan (in 1985) from the fruiting body of Lentinus edodes, and schizophyllan (in 1986) from a component in the cultured medium of Schizophyllum commune, have been developed from medicinal and edible mushrooms. The artificial cultivation of mushrooms and the tank cultur-ing method of processing their mycelium were established. Until recently, various kinds of healthy and functional foods developed from mushrooms such as Ganoderma lucidum, Grifola frondosa, Lentinus edodes, Agaricus blazei, A. bisporus, Hericium erinaceus, Inonotus obliquus, Sparasis crispa, etc. have appeared on the Japanese market. In 1998, the cultured mycelium product of Phellinus linteus (song gen or meshimakobu) had been developed as a medicinal in Korea. Also, in Japan, new products from the fruiting body and mycelium of Phellinus linteus are planned and expected to develop in the future. PB Begell House LK https://www.dl.begellhouse.com/journals/708ae68d64b17c52,684673684ea939cb,4a9b5eee5c1483b9.html