%0 Journal Article
%A Liu, Yong
%A Ma, Chaoyu
%A Zhang, Nu
%D 2018
%I Begell House
%K CD4, CD8, infection, IL-15, Memory, TGF-beta
%N 2
%P 79-103
%R 10.1615/CritRevImmunol.2018025653
%T Tissue-Specific Control of Tissue-Resident Memory T Cells
%U https://www.dl.begellhouse.com/journals/2ff21abf44b19838,443ae0ff4b5271d1,736f002a687dc8bd.html
%V 38
%X Tissue-resident memory T (TRM) cells have emerged as a major component of T cell biology. Recent investigations have greatly advanced our understanding of TRMs. Common features have been discovered to distinguish memory T cells residing in various mucosal and non-mucosal tissues from their circulating counterparts. Given that most organs and tissues contain a unique microenvironment, local signal-induced tissue-specific features are tightly associated with the differentiation, homeostasis, and protective functions of TRMs. Here, we discuss recent advances in the TRM field with a special emphasis on the interaction between local signals and TRMs in the context of individual tissue environment.
%8 2018-04-26