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Proceedings of CHT-15. 6th International Symposium on ADVANCES IN COMPUTATIONAL HEAT TRANSFER
May, 25-29, 2015, Rutgers University, New Brunswick, NJ, USA

DOI: 10.1615/ICHMT.2015.IntSympAdvComputHeatTransf


ISBN Print: 978-1-56700-429-8

ISSN: 2578-5486

NUMERICAL MODELING OF THE MOTION OF PARTICLES IN A BLOOD VESSEL: IMPLICATIONS FOR TARGETED DRUG DELIVERY

pages 1031-1037
DOI: 10.1615/ICHMT.2015.IntSympAdvComputHeatTransf.910
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RESUMO

In this paper, we describe a numerical model for the ab initio evaluation of particulateladen flow in a vessel. We consider the multiphase flow problem that simulates blood flow in a vessel in the context of drug delivery. The blood is considered non-Newtonian and the red blood cells are coarse grained by solid spheres in the model. By carefully matching the viscosities of real blood with that of the model fluid, we describe the rheology. The predicted flow profile shows excellent comparison with a Casson profile. This lends credibility to the numerical modeling. This study is useful for describing, in general, multiphase particulate laden flows.

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