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ISSN Печать: 0731-8898
ISSN Онлайн: 2162-6537
Indexed in
Black Tea (Camellia sinensis) as a Chemopreventive Agent in Oral Precancerous Lesions
Краткое описание
Oral carcinoma is the most common malignancy found in adult Indian men and the third most common in adult Indian women. About half of all cases are found to be associated with precancerous lesions, chiefly leukoplakia. We wanted to explore the possible benefits of black tea (Camellia sinensis) administered to patients with oral leukoplakia. Eighty-two subjects with oral leukoplakia underwent micronuclei and chromosomal assays on exfoliated oral mucosal epithelium, after which they received black tea in a fixed regimen. The micronuclei assay was repeated at 6 months, and the chromosomal study at 1 year. After the first year, the first 15 patients entered onto this study showed a significant decrease in the micronuclei frequency and chromosomal aberrations, which correlated with the clinical improvement. Several in vitro and animal studies have suggested the efficacy of tea in the chemoprevention of cancer. To the best of our knowledge, this is the first report on the effect of black tea in oral leukoplakia.
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Thomasset Sarah C., Berry David P., Garcea Giuseppe, Marczylo Timothy, Steward William P., Gescher Andreas J., Dietary polyphenolic phytochemicals—promising cancer chemopreventive agents in humans? A review of their clinical properties, International Journal of Cancer, 120, 3, 2007. Crossref
-
Babich Harvey, Gottesman Reena T., Liebling Emily J., Schuck Alyssa G., Theaflavin-3-Gallate and Theaflavin-3'-Gallate, Polyphenols in Black Tea with Prooxidant Properties, Basic & Clinical Pharmacology & Toxicology, 103, 1, 2008. Crossref
-
Ben-Arye E., Schiff E., Hassan E., Mutafoglu K., Lev-Ari S., Steiner M., Lavie O., Polliack A., Silbermann M., Lev E., Integrative oncology in the Middle East: from traditional herbal knowledge to contemporary cancer care, Annals of Oncology, 23, 1, 2012. Crossref
-
Wu C.D., Wei G., Tea as a functional food for oral health, in Food Constituents and Oral Health, 2009. Crossref
-
Babich Harvey, Schuck Alyssa G., Weisburg Jeffrey H., Zuckerbraun Harriet L., Research Strategies in the Study of the Pro-Oxidant Nature of Polyphenol Nutraceuticals, Journal of Toxicology, 2011, 2011. Crossref
-
Hardy Mary L., Dietary Supplement Use in Cancer Care: Help or Harm, Hematology/Oncology Clinics of North America, 22, 4, 2008. Crossref
-
Schuck Alyssa G., Ausubel Miriam B., Zuckerbraun Harriet L., Babich Harvey, Theaflavin-3,3′-digallate, a component of black tea: An inducer of oxidative stress and apoptosis, Toxicology in Vitro, 22, 3, 2008. Crossref
-
Scully C., Hegarty A., The Oral Cavity and Lips, in Rook's Textbook of Dermatology, 2010. Crossref
-
Wynn Susan G., Fougère Barbara J., Veterinary Herbal Medicine: A Systems-Based Approach, in Veterinary Herbal Medicine, 2007. Crossref
-
Nagini Siddavaram, Senthil Murugan Ramalingam, Cancer Chemoprevention by Black Tea Polyphenols, in Tea in Health and Disease Prevention, 2013. Crossref
-
Delaney Sarah, Wan Luke, O’Brien Peter J., Hepatocyte Cytotoxicity of Green Tea Phenolic Acids, Gallates, and Catechins, in Tea in Health and Disease Prevention, 2013. Crossref
-
Duffy Robert, Wade Christine, Chang Raymond, Discovery of anticancer drugs from antimalarial natural products: a MEDLINE literature review, Drug Discovery Today, 17, 17-18, 2012. Crossref
-
Varoni E.M., Iriti M., Odontoiatria e nutraceutica: applicazioni cliniche, Dental Cadmos, 82, 4, 2014. Crossref
-
Zhao Xin, Qian Yu, Zhou Ya-Lin, Wang Rui, Wang Qiang, Li Gui-Jie, Pu-erh Tea Has In Vitro Anticancer Activity in TCA8113 Cells and Preventive Effects on Buccal Mucosa Cancer in U14 Cells Injected Mice In Vivo, Nutrition and Cancer, 66, 6, 2014. Crossref
-
Ding Yijian, Yao Hua, Yao Yanan, Fai Leonard, Zhang Zhuo, Protection of Dietary Polyphenols against Oral Cancer, Nutrients, 5, 6, 2013. Crossref
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Lambert Joshua D., Kwon Seok-Joo, Hong Jungil, Yang Chung S., Salivary hydrogen peroxide produced by holding or chewing green tea in the oral cavity, Free Radical Research, 41, 7, 2007. Crossref
-
Sheweita Salah A., Wally Mona, Hassan Mostafa, Erectile Dysfunction Drugs Changed the Protein Expressions and Activities of Drug-Metabolising Enzymes in the Liver of Male Rats, Oxidative Medicine and Cellular Longevity, 2016, 2016. Crossref
-
Babich H., Selevan A. R., Ravkin E. R., Glutathione as a Mediator of theIn VitroCytotoxicity of a Green Tea Polyphenol Extract, Toxicology Mechanisms and Methods, 17, 6, 2007. Crossref
-
Matovina Chloe, Birkeland Andrew C., Zick Suzanna, Shuman Andrew G., Integrative Medicine in Head and Neck Cancer, Otolaryngology–Head and Neck Surgery, 156, 2, 2017. Crossref
-
Santos C.B., Bernardino G.Z., Soares F.J., Espindola J.D., Arruda P.M.R., Paula J.R., Conceição E.C., Bara M.T.F, Preparo e caracterização de tinturas das folhas de chá verde [Camellia sinensis (L.) O. Kuntze] Theaceae, Revista Brasileira de Plantas Medicinais, 16, 4, 2014. Crossref
-
Miller Wendy A., Wuertz Beverly R., Ondrey Frank G., PPARγ-Mediated p21 Induction in Aerodigestive Preneoplastic Cell Lines, Annals of Otology, Rhinology & Laryngology, 127, 10, 2018. Crossref
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Nimbalkar Vaishnavi K., Manna Subhakankha, Maru Girish B., Mahimkar Manoj B., Head and Neck Cancer Prevention by Phytochemicals: Current Status and Challenges, Current Pharmacology Reports, 6, 3, 2020. Crossref
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Balappanavar Aswini, Tea and Oral Health, in Tea - Chemistry and Pharmacology [Working Title], 2020. Crossref
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Mok T.S.K., Yeo W., Johnson P.J., Hui P., Ho W.M., Lam K.C., Xu M., Chak K., Chan A., Wong H., Mo F., Zee B., A double-blind placebo-controlled randomized study of Chinese herbal medicine as complementary therapy for reduction of chemotherapy-induced toxicity, Annals of Oncology, 18, 4, 2007. Crossref
-
Quero Javier, Mármol Inés, Cerrada Elena, Rodríguez-Yoldi María Jesús, Insight into the potential application of polyphenol-rich dietary intervention in degenerative disease management, Food & Function, 11, 4, 2020. Crossref
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Krishna Jillella Gopala, Ojha Probir Kumar, Artificial Neural Network (ANN) Modeling of Odor Threshold Property of Diverse Chemical Constituents of Black Tea and Coffee, in Research Anthology on Artificial Neural Network Applications, 2022. Crossref
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Nagi Ravleen, Therapeutic Role of Phytochemicals in the Prevention of Oral Potentially Malignant Disorders and Oral Cancer – A Review, Journal of Evolution of Medical and Dental Sciences, 10, 16, 2021. Crossref
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