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Journal of Environmental Pathology, Toxicology and Oncology
Главный редактор: Qian Peng (open in a new tab)

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ISSN Печать: 0731-8898

ISSN Онлайн: 2162-6537

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.4 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.8 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.5 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00049 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.59 SJR: 0.429 SNIP: 0.507 CiteScore™:: 3.9 H-Index: 49

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Antioxidant and Radiation Antagonistic Effect of Saraca indica

Том 29, Выпуск 1, 2010, pp. 69-79
DOI: 10.1615/JEnvironPatholToxicolOncol.v29.i1.90
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Краткое описание

The present study was undertaken to investigate the radiation mitigating effect of hydro-alcoholic extract of Saraca indica (SIE) against mice exposed to whole body gamma radiation. Free radical scavenging ability by SIE was demonstrated using hydroxyl, superoxide anion, ABTS•+ and DPPH radicals generated in vitro. A significant increase in the animal survival (dose reduction factor = 1.39), inhibition in the decline of hematological parameters as well as increased number of spleen colony-forming units was observed when SIE was administered prior to radiation. SIE pretreatment increased the levels of glutathione, glutathione S- trans-ferase, catalase and lowered lipid peroxidation. Our findings for the first time demonstrate the protective potential of SIE against radiation induced syndromes with an optimal dose of 400 mg/kg b.wt. The radiation mitigating effect may be attributed to the mechanisms such as free radical scavenging, elevation in antioxidant status, and reduction in lipid peroxidation.

ЦИТИРОВАНО В
  1. P.R Archana, Rao B. Nageshwar, Rao B.S. Satish, In vivo radioprotective potential of thymol, a monoterpene phenol derivative of cymene, Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 726, 2, 2011. Crossref

  2. Das Shubhankar, Kumar Rishikesh, Rao Bola Sadashiva Satish, Radio-modifying potential ofSaraca indicaagainst ionizing radiation: an in vitro study using Chinese hamster lung fibroblast (V79) cells, Cell Biology International, 39, 9, 2015. Crossref

  3. Jagetia Ganesh Chandra, Shetty Prakash Chandra, Vidyasagar Mamidipudi Srinivasa, Inhibition of Radiation-Induced DNA Damage by Jamun, Syzygium cumini, in the Cultured Splenocytes of Mice Exposed to Different Doses of γ-Radiation, Integrative Cancer Therapies, 11, 2, 2012. Crossref

  4. Kumar Amith, Kumarchandra Reshma, Rai Rajalakshmi, Kumblekar Vasavi, Radiation mitigating activities of Psidium guajava L. against whole-body X-ray-induced damages in albino Wistar rat model, 3 Biotech, 10, 12, 2020. Crossref

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